6E43
Crystal structure of human indoleamine 2,3-dioxygenase 1 (IDO1) in complex with a BMS-978587 analog
Summary for 6E43
Entry DOI | 10.2210/pdb6e43/pdb |
Descriptor | Indoleamine 2,3-dioxygenase 1, (1R,2S)-2-(4-[cyclohexyl(2-methylpropyl)amino]-3-{[(4-methylphenyl)carbamoyl]amino}phenyl)cyclopropane-1-carboxylic acid, BENZOIC ACID, ... (4 entities in total) |
Functional Keywords | ido1, bms-978587 analog, inhibitor complex, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 183546.52 |
Authors | |
Primary citation | Luo, S.,Xu, K.,Xiang, S.,Chen, J.,Chen, C.,Guo, C.,Tong, Y.,Tong, L. High-resolution structures of inhibitor complexes of human indoleamine 2,3-dioxygenase 1 in a new crystal form. Acta Crystallogr F Struct Biol Commun, 74:717-724, 2018 Cited by PubMed: 30387777DOI: 10.1107/S2053230X18012955 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.705 Å) |
Structure validation
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