5DTI

Crystal structure of mouse acetylcholinesterase

Summary for 5DTI

• Entry DOI: 10.2210/pdb5dti/pdb
• Related: 5DTG 5DTJ
• Descriptor: Acetylcholinesterase (2 entities in total)
• Functional Keywords: hydrolase
• Biological source: Mus musculus (Mouse)
• Cellular location: Cell junction, synapse. Isoform H: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side: P21836
• Total number of polymer chains: 2
• Total formula weight: 120013.57

Authors

Tran, T.H.,Tong, L. (deposition date: 2015-09-18, release date: 2015-10-21, Last modification date: 2023-09-27)

• Primary citation: Katz, F.S.,Pecic, S.,Tran, T.H.,Trakht, I.,Schneider, L.,Zhu, Z.,Ton-That, L.,Luzac, M.,Zlatanic, V.,Damera, S.,Macdonald, J.,Landry, D.W.,Tong, L.,Stojanovic, M.N.; Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates.; Chembiochem, 16:2205-2215, 2015; PubMed: 26350723; DOI: 10.1002/cbic.201500348

Experimental method

X-RAY DIFFRACTION (2.003 Å)