5DTJ
Crystal Structure of dfp-inhibited mouse acetylcholinesterase in complex with the reactivator SP-134
Summary for 5DTJ
Entry DOI | 10.2210/pdb5dtj/pdb |
Related | 5DTG 5DTI |
Descriptor | Acetylcholinesterase, 1-[5-(2,4-dichlorophenoxy)pentyl]-1H-imidazole (2 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 2 |
Total formula weight | 121454.46 |
Authors | Tran, T.H.,Tong, L. (deposition date: 2015-09-18, release date: 2015-10-21, Last modification date: 2023-09-27) |
Primary citation | Katz, F.S.,Pecic, S.,Tran, T.H.,Trakht, I.,Schneider, L.,Zhu, Z.,Ton-That, L.,Luzac, M.,Zlatanic, V.,Damera, S.,Macdonald, J.,Landry, D.W.,Tong, L.,Stojanovic, M.N. Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates. Chembiochem, 16:2205-2215, 2015 Cited by PubMed: 26350723DOI: 10.1002/cbic.201500348 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
Download full validation report