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5A49
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BU of 5a49 by Molmil
Crystal structure of the LOTUS domain (aa 139-222) of Drosophila Oskar in C222
Descriptor: MATERNAL EFFECT PROTEIN OSKAR
Authors:Jeske, M, Glatt, S, Ephrussi, A, Mueller, C.W.
Deposit date:2015-06-05
Release date:2015-07-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.098 Å)
Cite:The Crystal Structure of the Drosophila Germline Inducer Oskar Identifies Two Domains with Distinct Vasa Helicase-and RNA-Binding Activities.
Cell Rep., 12, 2015
1K1B
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BU of 1k1b by Molmil
Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family
Descriptor: B-cell lymphoma 3-encoded protein
Authors:Michel, F, Soler-Lopez, M, Petosa, C, Cramer, P, Siebenlist, U, Mueller, C.W.
Deposit date:2001-09-24
Release date:2001-11-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family.
EMBO J., 20, 2001
7Z0O
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BU of 7z0o by Molmil
Structure of transcription factor UAF in complex with TBP and 35S rRNA promoter DNA
Descriptor: Histone H3, Histone H4, Non-template DNA, ...
Authors:Baudin, F, Murciano, B, Fung, H.K.H, Fromm, S.A, Mueller, C.W.
Deposit date:2022-02-23
Release date:2022-04-27
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism of RNA polymerase I selection by transcription factor UAF.
Sci Adv, 8, 2022
6HN4
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BU of 6hn4 by Molmil
Leucine-zippered human insulin receptor ectodomain with single bound insulin - "lower" membrane-proximal part
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor,Insulin receptor,General control protein GCN4
Authors:Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C.
Deposit date:2018-09-14
Release date:2018-11-21
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The signalling conformation of the insulin receptor ectodomain.
Nat Commun, 9, 2018
6HN5
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BU of 6hn5 by Molmil
Leucine-zippered human insulin receptor ectodomain with single bound insulin - "upper" membrane-distal part
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ...
Authors:Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C.
Deposit date:2018-09-14
Release date:2018-11-21
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The signalling conformation of the insulin receptor ectodomain.
Nat Commun, 9, 2018
6HGC
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BU of 6hgc by Molmil
Structure of Calypso in complex with DEUBAD of ASX
Descriptor: Polycomb protein Asx, Ubiquitin carboxyl-terminal hydrolase calypso,Ubiquitin carboxyl-terminal hydrolase calypso
Authors:De, I, Chittock, E.C, Groetsch, H, Miller, T.C.R, McCarthy, A.A, Mueller, C.W.
Deposit date:2018-08-23
Release date:2019-01-23
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structural Basis for the Activation of the Deubiquitinase Calypso by the Polycomb Protein ASX.
Structure, 27, 2019
7OBB
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BU of 7obb by Molmil
Cryo-EM structure of human RNA Polymerase I Open Complex
Descriptor: DNA non-template strand, DNA template strand, DNA-directed RNA polymerase I subunit RPA1, ...
Authors:Misiaszek, A.D, Girbig, M, Mueller, C.W.
Deposit date:2021-04-21
Release date:2021-12-08
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures of human RNA polymerase I.
Nat.Struct.Mol.Biol., 28, 2021
7OB9
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BU of 7ob9 by Molmil
Cryo-EM structure of human RNA Polymerase I in elongation state
Descriptor: DNA non-template strand, DNA template strand, DNA-directed RNA polymerase I subunit RPA1, ...
Authors:Misiaszek, A.D, Girbig, M, Mueller, C.W.
Deposit date:2021-04-21
Release date:2021-12-08
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structures of human RNA polymerase I.
Nat.Struct.Mol.Biol., 28, 2021
7OBA
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BU of 7oba by Molmil
Cryo-EM structure of human RNA Polymerase I in complex with RRN3
Descriptor: DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA2, ...
Authors:Misiaszek, A.D, Girbig, M, Mueller, C.W.
Deposit date:2021-04-21
Release date:2021-12-08
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structures of human RNA polymerase I.
Nat.Struct.Mol.Biol., 28, 2021
7OZR
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BU of 7ozr by Molmil
Subtomogram average of authentic mumps virus nucleocapsid from HeLa cell lysate of long helical pitch
Descriptor: Nucleocapsid, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3')
Authors:Mahamid, J, Zhang, X.
Deposit date:2021-06-28
Release date:2023-03-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Molecular mechanisms of stress-induced reactivation in mumps virus condensates.
Cell, 186, 2023
6F42
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BU of 6f42 by Molmil
RNA Polymerase III closed complex CC1.
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Vorlaender, M.K, Khatter, H, Wetzel, R, Hagen, W.J.H, Mueller, C.W.
Deposit date:2017-11-29
Release date:2018-01-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Molecular mechanism of promoter opening by RNA polymerase III.
Nature, 553, 2018
6F41
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BU of 6f41 by Molmil
RNA Polymerase III initially transcribing complex
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Vorlaender, M.K, Khatter, H, Wetzel, R, Hagen, W.J.H, Mueller, C.W.
Deposit date:2017-11-29
Release date:2018-01-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular mechanism of promoter opening by RNA polymerase III.
Nature, 553, 2018
2X6U
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BU of 2x6u by Molmil
Crystal structure of human TBX5 in the DNA-free form
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, MAGNESIUM ION, T-BOX TRANSCRIPTION FACTOR TBX5
Authors:Stirnimann, C.U, Mueller, C.W.
Deposit date:2010-02-22
Release date:2010-04-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form.
J.Mol.Biol., 400, 2010
6F40
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BU of 6f40 by Molmil
RNA Polymerase III open complex
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Vorlaender, M.K, Khatter, H, Wetzel, R, Hagen, W.J.H, Mueller, C.W.
Deposit date:2017-11-29
Release date:2018-01-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular mechanism of promoter opening by RNA polymerase III.
Nature, 553, 2018
6F44
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BU of 6f44 by Molmil
RNA Polymerase III closed complex CC2.
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Vorlaender, M.K, Khatter, H, Wetzel, R, Hagen, W.J.H, Mueller, C.W.
Deposit date:2017-11-29
Release date:2018-01-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Molecular mechanism of promoter opening by RNA polymerase III.
Nature, 553, 2018
2XYI
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BU of 2xyi by Molmil
Crystal Structure of Nurf55 in complex with a H4 peptide
Descriptor: DI(HYDROXYETHYL)ETHER, HISTONE H4, PROBABLE HISTONE-BINDING PROTEIN CAF1, ...
Authors:Stirnimann, C.U, Nowak, A.J, Mueller, C.W.
Deposit date:2010-11-17
Release date:2011-05-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Chromatin-Modifying Complex Component Nurf55/P55 Associates with Histones H3, H4 and Polycomb Repressive Complex 2 Subunit Su(Z)12 Through Partially Overlapping Binding Sites.
J.Biol.Chem., 286, 2011
2X6V
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BU of 2x6v by Molmil
Crystal structure of human TBX5 in the DNA-bound and DNA-free form
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 5'-D(*TP*AP*AP*GP*GP*TP*GP*TP*GP*AP*GP)-3', 5'-D(*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP)-3', ...
Authors:Ptchelkine, D, Stirnimann, C.U, Grimm, C, Mueller, C.W.
Deposit date:2010-02-22
Release date:2010-04-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form.
J.Mol.Biol., 400, 2010
5M2N
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BU of 5m2n by Molmil
Crystal Structure of Elongator subunit Elp2
Descriptor: Elongator complex protein 2
Authors:Glatt, S, Mueller, C.W.
Deposit date:2016-10-13
Release date:2016-12-28
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.812 Å)
Cite:Architecture of the yeast Elongator complex.
EMBO Rep., 18, 2017
5NT7
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BU of 5nt7 by Molmil
Structure of the LOTUS domain of Oskar in complex with the C-terminal RecA-like domain of Vasa
Descriptor: ATP-dependent RNA helicase vasa, isoform A, Maternal effect protein oskar
Authors:Jeske, M, Ephrussi, A, Mueller, C.W.
Deposit date:2017-04-27
Release date:2017-05-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The LOTUS domain is a conserved DEAD-box RNA helicase regulator essential for the recruitment of Vasa to the germ plasm and nuage.
Genes Dev., 31, 2017
1BVO
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BU of 1bvo by Molmil
DORSAL HOMOLOGUE GAMBIF1 BOUND TO DNA
Descriptor: DNA DUPLEX, TRANSCRIPTION FACTOR GAMBIF1
Authors:Cramer, P, Varrot, A, Barillas-Mury, C, Kafatos, F.C, Mueller, C.W.
Deposit date:1998-09-16
Release date:1999-07-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the specificity domain of the Dorsal homologue Gambif1 bound to DNA.
Structure Fold.Des., 7, 1999
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