1BVO

DORSAL HOMOLOGUE GAMBIF1 BOUND TO DNA

Summary for 1BVO

• Entry DOI: 10.2210/pdb1bvo/pdb
• Descriptor: DNA DUPLEX, TRANSCRIPTION FACTOR GAMBIF1, ... (4 entities in total)
• Functional Keywords: transcription factor, rel protein, morphogen, immunity, development, insects, complex (transcription factor-dna), complex (transcription factor-dna) complex, complex (transcription factor/dna)
• Biological source: Anopheles gambiae (African malaria mosquito)
• Total number of polymer chains: 3
• Total formula weight: 28806.43

Authors

Cramer, P.,Varrot, A.,Barillas-Mury, C.,Kafatos, F.C.,Mueller, C.W. (deposition date: 1998-09-16, release date: 1999-07-12, Last modification date: 2024-11-13)

Primary citation

Cramer, P.,Varrot, A.,Barillas-Mury, C.,Kafatos, F.C.,Muller, C.W.
Structure of the specificity domain of the Dorsal homologue Gambif1 bound to DNA.
Structure Fold.Des., 7:841-852, 1999

PubMed Abstract: NF-kappa B/Rel transcription factors play important roles in immunity and development in mammals and insects. Their activity is regulated by their cellular localization, homo- and heterodimerization and association with other factors on their target gene promoters. Gambif1 from Anopheles gambiae is a member of the Rel family and a close homologue of the morphogen Dorsal, which establishes dorsoventral polarity in the Drosophila embryo.

PubMed: 10425685
DOI: 10.1016/S0969-2126(99)80107-5

Experimental method

X-RAY DIFFRACTION (2.7 Å)