5NT7

Structure of the LOTUS domain of Oskar in complex with the C-terminal RecA-like domain of Vasa

Summary for 5NT7

Entry DOI	10.2210/pdb5nt7/pdb
Descriptor	ATP-dependent RNA helicase vasa, isoform A, Maternal effect protein oskar (3 entities in total)
Functional Keywords	dead-box rna helicase, atpase, rna binding, regulator, stimulator, germ plasm, nuage, lotus, hydrolase- hydrolase regulator complex, hydrolase-hydrolase regulator complex, hydrolase/hydrolase regulator
Biological source	Drosophila melanogaster (Fruit fly) More
Cellular location	Cytoplasm : P09052
Total number of polymer chains	4
Total formula weight	60330.31
Authors	Jeske, M.,Ephrussi, A.,Mueller, C.W. (deposition date: 2017-04-27, release date: 2017-05-17, Last modification date: 2024-01-17)
Primary citation	Jeske, M.,Muller, C.W.,Ephrussi, A. The LOTUS domain is a conserved DEAD-box RNA helicase regulator essential for the recruitment of Vasa to the germ plasm and nuage. Genes Dev., 31:939-952, 2017 Cited by PubMed: 28536148 DOI: 10.1101/gad.297051.117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation