7OBB
Cryo-EM structure of human RNA Polymerase I Open Complex
Summary for 7OBB
Entry DOI | 10.2210/pdb7obb/pdb |
EMDB information | 12797 |
Descriptor | DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerases I and III subunit RPAC2, DNA-directed RNA polymerases I, II, and III subunit RPABC4, ... (16 entities in total) |
Functional Keywords | rna polymerase i, human, rrna transcription, dna-dependent rna polymerase, pre-initiation, open complex, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 15 |
Total formula weight | 629781.88 |
Authors | Misiaszek, A.D.,Girbig, M.,Mueller, C.W. (deposition date: 2021-04-21, release date: 2021-12-08, Last modification date: 2021-12-22) |
Primary citation | Misiaszek, A.D.,Girbig, M.,Grotsch, H.,Baudin, F.,Murciano, B.,Lafita, A.,Muller, C.W. Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28:997-1008, 2021 Cited by PubMed: 34887565DOI: 10.1038/s41594-021-00693-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
Download full validation report