7OB9

Cryo-EM structure of human RNA Polymerase I in elongation state

Summary for 7OB9

• Entry DOI: 10.2210/pdb7ob9/pdb
• EMDB information: 12795
• Descriptor: DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerases I and III subunit RPAC2, DNA-directed RNA polymerases I, II, and III subunit RPABC4, ... (18 entities in total)
• Functional Keywords: rna polymerase i, human, rrna transcription, dna-dependent rna polymerase, elongation state, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 16
• Total formula weight: 639016.38

Authors

Misiaszek, A.D.,Girbig, M.,Mueller, C.W. (deposition date: 2021-04-21, release date: 2021-12-08, Last modification date: 2021-12-22)

• Primary citation: Misiaszek, A.D.,Girbig, M.,Grotsch, H.,Baudin, F.,Murciano, B.,Lafita, A.,Muller, C.W.; Cryo-EM structures of human RNA polymerase I.; Nat.Struct.Mol.Biol., 28:997-1008, 2021; PubMed: 34887565; DOI: 10.1038/s41594-021-00693-4

Experimental method

ELECTRON MICROSCOPY (2.7 Å)