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2X6V

Crystal structure of human TBX5 in the DNA-bound and DNA-free form

Summary for 2X6V
Entry DOI10.2210/pdb2x6v/pdb
Related2X6U
DescriptorT-BOX TRANSCRIPTION FACTOR TBX5, 5'-D(*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP)-3', 5'-D(*TP*AP*AP*GP*GP*TP*GP*TP*GP*AP*GP)-3', ... (6 entities in total)
Functional Keywordstranscription-dna complex, holt-oram-syndrome, developmental protein, transcription regulation, repressor, dna-binding, transcription, nuclear protein, transcription/dna
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationNucleus (Potential): Q99593
Total number of polymer chains4
Total formula weight53912.64
Authors
Ptchelkine, D.,Stirnimann, C.U.,Grimm, C.,Mueller, C.W. (deposition date: 2010-02-22, release date: 2010-04-28, Last modification date: 2023-12-20)
Primary citationStirnimann, C.U.,Ptchelkine, D.,Grimm, C.,Muller, C.W.
Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form.
J.Mol.Biol., 400:71-, 2010
Cited by
PubMed: 20450920
DOI: 10.1016/J.JMB.2010.04.052
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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