2X6V

Crystal structure of human TBX5 in the DNA-bound and DNA-free form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	T-BOX TRANSCRIPTION FACTOR TBX5	polymer	203	23406.1	2	UniProt (Q99593) Pfam (PF00907) In PDB	HOMO SAPIENS (HUMAN)	T-BOX PROTEIN 5, HUMAN TBX5
2	C	5'-D(*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP)-3'	polymer	11	3244.1	1		SYNTHETIC CONSTRUCT
3	D	5'-D(*TP*AP*AP*GP*GP*TP*GP*TP*GP*AP*GP)-3'	polymer	11	3453.3	1		SYNTHETIC CONSTRUCT
4	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	B	2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL	non-polymer		354.4	1	Chemie (PE4)
6		water	water		18.0	368	Chemie (HOH)

Sequence modifications

A, B: 49 - 50 (PDB: 2X6V)
A, B: 51 - 251 (UniProt: Q99593)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	53509.6
Non-Polymers*	Number of molecules	3
	Total formula weight	403.0
All*	Total formula weight	53912.6

*Water molecules are not included.