2X6U
Crystal structure of human TBX5 in the DNA-free form
Summary for 2X6U
Entry DOI | 10.2210/pdb2x6u/pdb |
Related | 2X6V |
Descriptor | T-BOX TRANSCRIPTION FACTOR TBX5, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | developmental protein, dna-binding, holt-oram-syndrome, ig-fold, nuclear protein, repressor, tbx3, transcription, transcription regulation |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus (Potential): Q99593 |
Total number of polymer chains | 1 |
Total formula weight | 23857.75 |
Authors | Stirnimann, C.U.,Mueller, C.W. (deposition date: 2010-02-22, release date: 2010-04-28, Last modification date: 2024-05-08) |
Primary citation | Stirnimann, C.U.,Ptchelkine, D.,Grimm, C.,Muller, C.W. Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form. J.Mol.Biol., 400:71-, 2010 Cited by PubMed: 20450920DOI: 10.1016/J.JMB.2010.04.052 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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