2O0O
 
 | | Crystal structure of TL1A | | Descriptor: | MAGNESIUM ION, TNF superfamily ligand TL1A | | Authors: | Jin, T.C, Kim, S, Guo, F, Howard, A.J, Zhang, Y.Z. | | Deposit date: | 2006-11-27 | | Release date: | 2007-10-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-ray crystal structure of TNF ligand family member TL1A at 2.1A.
Biochem.Biophys.Res.Commun., 364, 2007
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6N5S
 | | Structure of Human pir-miRNA-320b-2 Apical Loop and One-base-pair Stem Fused to the YdaO Riboswitch Scaffold | | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Shoffner, G.M, Peng, Z, Guo, F. | | Deposit date: | 2018-11-22 | | Release date: | 2019-11-27 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.802 Å) | | Cite: | Three-dimensional structures of pri-miRNA apical junctions and loops revealed by scaffold-directed crystallography
To Be Published
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6N5N
 | | Structure of Human pir-miRNA-208a Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold | | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, POTASSIUM ION, ... | | Authors: | Shoffner, G.M, Peng, Z, Guo, F. | | Deposit date: | 2018-11-22 | | Release date: | 2019-11-27 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.951 Å) | | Cite: | Three-dimensional structures of pri-miRNA apical junctions and loops revealed by scaffold-directed crystallography
To Be Published
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6N5Q
 | | Structure of Human pir-miRNA-378a Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold | | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, POTASSIUM ION, ... | | Authors: | Shoffner, G.M, Peng, Z, Guo, F. | | Deposit date: | 2018-11-22 | | Release date: | 2019-11-27 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.946 Å) | | Cite: | Three-dimensional structures of pri-miRNA apical junctions and loops revealed by scaffold-directed crystallography
To Be Published
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2NML
 | | Crystal structure of HEF2/ERH at 1.55 A resolution | | Descriptor: | Enhancer of rudimentary homolog | | Authors: | Jin, T.C, Guo, F, Serebriiskii, I.G, Howard, A.J, Zhang, Y.Z. | | Deposit date: | 2006-10-21 | | Release date: | 2006-10-31 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | A 1.55 A resolution X-ray crystal structure of HEF2/ERH and insights into its transcriptional and cell-cycle interaction networks.
Proteins, 68, 2007
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2CRX
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1XO0
 | | High resolution structure of the holliday junction intermediate in cre-loxp site-specific recombination | | Descriptor: | Recombinase CRE, loxP | | Authors: | Ghosh, K, Lau, C.K, Guo, F, Segall, A.M, Van Duyne, G.D. | | Deposit date: | 2004-10-05 | | Release date: | 2004-12-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination.
J.Biol.Chem., 280, 2005
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1XNS
 | | Peptide trapped Holliday junction intermediate in Cre-loxP recombination | | Descriptor: | Recombinase CRE, loxP DNA | | Authors: | Ghosh, K, Lau, C.K, Guo, F, Segall, A.M, Van Duyne, G.D. | | Deposit date: | 2004-10-05 | | Release date: | 2004-12-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination.
J.Biol.Chem., 280, 2005
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4Y5X
 | | Diabody 305 complex with EpoR | | Descriptor: | CITRATE ANION, DI(HYDROXYETHYL)ETHER, Erythropoietin receptor, ... | | Authors: | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | | Deposit date: | 2015-02-12 | | Release date: | 2015-03-18 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
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4Y5Y
 | | Diabody 330 complex with EpoR | | Descriptor: | Erythropoietin receptor, GLYCEROL, diabody 330 VH domain, ... | | Authors: | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | | Deposit date: | 2015-02-12 | | Release date: | 2015-03-18 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
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4Y5V
 | | Diabody 305 complex with EpoR | | Descriptor: | DI(HYDROXYETHYL)ETHER, Diabody 305 VL domain, Erythropoietin receptor, ... | | Authors: | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | | Deposit date: | 2015-02-12 | | Release date: | 2015-04-29 | | Method: | X-RAY DIFFRACTION (2.604 Å) | | Cite: | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
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8JX6
 | | Deep-Sea Helicase 9 (DSH9) | | Descriptor: | Deep-Sea Helicase 9, L(+)-TARTARIC ACID, MAGNESIUM ION | | Authors: | Wang, L, Liu, Z, Guo, F. | | Deposit date: | 2023-06-30 | | Release date: | 2023-07-26 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of Deep-Sea Helicase 9 (DSH9)
To Be Published
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7YFH
 | | Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine, glutamate and (R)-PYD-106 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | | Authors: | Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S. | | Deposit date: | 2022-07-08 | | Release date: | 2023-03-29 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
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7YFG
 | | Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine and glutamate (major class in asymmetry) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | | Authors: | Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S. | | Deposit date: | 2022-07-08 | | Release date: | 2023-03-29 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
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7YFI
 | | Structure of the Rat tri-heteromeric GluN1-GluN2A-GluN2C NMDA receptor in complex with glycine and glutamate | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | | Authors: | Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S. | | Deposit date: | 2022-07-08 | | Release date: | 2023-03-29 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
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7Y4G
 | | sit-bound btDPP4 | | Descriptor: | (2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-A MINE, btDPP4 | | Authors: | Hang, J, Jiang, C, Wang, K, Zhang, Z, Guo, F, Liu, J, Wang, G, Lei, X, Gonzalez, F, Qiao, J. | | Deposit date: | 2022-06-14 | | Release date: | 2023-06-14 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Microbial-host-isozyme analyses reveal microbial DPP4 as a potential antidiabetic target.
Science, 381, 2023
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7Y4F
 | | bacterial DPP4 | | Descriptor: | Dipeptidyl peptidase IV | | Authors: | Hang, J, Jiang, C, Wang, K, Zhang, Z, Guo, F, Liu, J, Wang, G, Lei, X, Gonzalez, F, Qiao, J. | | Deposit date: | 2022-06-14 | | Release date: | 2023-06-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.918 Å) | | Cite: | Microbial-host-isozyme analyses reveal microbial DPP4 as a potential antidiabetic target.
Science, 381, 2023
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4WO9
 | | Lysozyme Post-Surface Acoustic Waves | | Descriptor: | Lysozyme C, SODIUM ION | | Authors: | French, J.B. | | Deposit date: | 2014-10-15 | | Release date: | 2015-02-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4WOC
 | | Proteinase-K Post-Surface Acoustic Waves | | Descriptor: | Proteinase K, SULFATE ION | | Authors: | French, J.B. | | Deposit date: | 2014-10-15 | | Release date: | 2015-02-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.601 Å) | | Cite: | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4WO6
 | | Lysozyme Pre-surface acoustic wave | | Descriptor: | Lysozyme C, SODIUM ION | | Authors: | French, J.B. | | Deposit date: | 2014-10-15 | | Release date: | 2015-02-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.001 Å) | | Cite: | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4WOB
 | | Proteinase-K Pre-Surface Acoustic Wave | | Descriptor: | Proteinase K, SULFATE ION | | Authors: | French, J.B. | | Deposit date: | 2014-10-15 | | Release date: | 2015-02-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4WOA
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4FHZ
 | | Crystal structure of a carboxyl esterase at 2.0 angstrom resolution | | Descriptor: | DI(HYDROXYETHYL)ETHER, Phospholipase/Carboxylesterase, SODIUM ION | | Authors: | Wu, L, Ma, J, Zhou, J, Yu, H. | | Deposit date: | 2012-06-07 | | Release date: | 2012-10-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution.
Appl.Microbiol.Biotechnol., 97, 2013
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7LTU
 | | AALALL SEGMENT FROM THE NUCLEOPROTEIN OF SARS-COV-2, RESIDUES 217-222, CRYSTAL FORM 1 | | Descriptor: | AALALL SEGMENT FROM THE NUCLEOPROTEIN OF SARS-COV-2,RESIDUES 217-222, trifluoroacetic acid | | Authors: | Zee, C.-T, Sawaya, M.R, Rodriguez, J.A, Eisenberg, D.S. | | Deposit date: | 2021-02-20 | | Release date: | 2021-03-17 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.122 Å) | | Cite: | Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2.
Biorxiv, 2021
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7LUX
 | | AALALL segment from the Nucleoprotein of SARS-CoV-2, residues 217-222, crystal form 2 | | Descriptor: | Nucleoprotein AALALL, TETRAETHYLENE GLYCOL | | Authors: | Lu, J, Zee, C.-T, Sawaya, M.R, Rodriguez, J.A, Eisenberg, D.S. | | Deposit date: | 2021-02-23 | | Release date: | 2021-03-17 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.303 Å) | | Cite: | Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2.
Biorxiv, 2021
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