4Y5Y

Diabody 330 complex with EpoR

Summary for 4Y5Y

• Entry DOI: 10.2210/pdb4y5y/pdb
• Related: 4Y5V 4Y5X
• Descriptor: diabody 330 VH domain, diabody 330 VL domain, Erythropoietin receptor, ... (5 entities in total)
• Functional Keywords: diabody complex, receptor, protein binding-immune system complex, protein binding/immune system
• Biological source: Homo sapiens; More
• Cellular location: Cell membrane; Single-pass type I membrane protein. Isoform EPOR-S: Secreted : P19235
• Total number of polymer chains: 6
• Total formula weight: 102428.44

Authors

Moraga, I.,Guo, F.,Ozkan, E.,Jude, K.M.,Garcia, K.C. (deposition date: 2015-02-12, release date: 2015-03-18, Last modification date: 2023-09-27)

• Primary citation: Moraga, I.,Wernig, G.,Wilmes, S.,Gryshkova, V.,Richter, C.P.,Hong, W.J.,Sinha, R.,Guo, F.,Fabionar, H.,Wehrman, T.S.,Krutzik, P.,Demharter, S.,Plo, I.,Weissman, I.L.,Minary, P.,Majeti, R.,Constantinescu, S.N.,Piehler, J.,Garcia, K.C.; Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.; Cell, 160:1196-1208, 2015; PubMed: 25728669; DOI: 10.1016/j.cell.2015.02.011

Experimental method

X-RAY DIFFRACTION (2.85 Å)