4Y5Y
Diabody 330 complex with EpoR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | diabody 330 VH domain | polymer | 130 | 13941.5 | 2 | Homo sapiens | ||
2 | B, E | diabody 330 VL domain | polymer | 117 | 12016.1 | 2 | Homo sapiens | ||
3 | C, F | Erythropoietin receptor | polymer | 229 | 25210.6 | 2 | UniProt (P19235) Pfam (PF09067) Pfam (PF00041) In PDB | Homo sapiens (Human) | EPO-R |
4 | C | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
C, F: 8 - 225 (UniProt: P19235)
PDB | External Database | Details |
---|---|---|
Phe 3 | - | expression tag |
Ala 4 | - | expression tag |
Gly 5 | - | expression tag |
Ser 6 | - | expression tag |
Ala 7 | - | expression tag |
Gln 52 | Asn 76 | engineered mutation |
Gln 164 | Asn 188 | engineered mutation |
Leu 223 | Asp 247 | engineered mutation |
Asp 224 | Leu 248 | engineered mutation |
Lys 226 | - | expression tag |
Glu 227 | - | expression tag |
Lys 228 | - | expression tag |
Ala 229 | - | expression tag |
Ala 230 | - | expression tag |
Ala 231 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 102336.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 92.1 | |
All* | Total formula weight | 102428.4 |