6IUR

A phosphatase complex STRN3-PP2Aa

Summary for 6IUR

Entry DOI	10.2210/pdb6iur/pdb
Descriptor	PP2A scaffolding subunit, Striatin-3, PROPANE, ... (4 entities in total)
Functional Keywords	phosphatase, complex, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	8
Total formula weight	285389.42
Authors	Tang, Y.,Zhou, Z.C. (deposition date: 2018-11-30, release date: 2019-12-04, Last modification date: 2023-11-22)
Primary citation	Tang, Y.,Fang, G.,Guo, F.,Zhang, H.,Chen, X.,An, L.,Chen, M.,Zhou, L.,Wang, W.,Ye, T.,Zhou, L.,Nie, P.,Yu, H.,Lin, M.,Zhao, Y.,Lin, X.,Yuan, Z.,Jiao, S.,Zhou, Z. Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer. Cancer Cell, 38:115-128.e9, 2020 Cited by PubMed: 32589942 DOI: 10.1016/j.ccell.2020.05.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.33 Å)

Structure validation