7YVG
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH132 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH132 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVK
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH272 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH272 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVO
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH027/132 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH132 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVH
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH132 Fab | Descriptor: | Spike glycoprotein, TH132 Fab heavy chain, TH132 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVM
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH272 Fab | Descriptor: | Spike glycoprotein, TH281 Fab heavy chain, TH281 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVF
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH027 Fab | Descriptor: | Spike glycoprotein, TH027 Fab heavy chain, TH027 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7W5K
| The C296A mutant of L-sorbosone dehydrogenase (SNDH) from Gluconobacter Oxydans WSH-004 | Descriptor: | L-sorbosone dehydrogenase, NAD(P) dependent, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Li, D, Hou, X.D, Rao, Y.J, Zhou, J.W, Chen, J. | Deposit date: | 2021-11-30 | Release date: | 2023-03-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase. Adv Sci, 10, 2023
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8OL9
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7DUU
| Crystal structure of HLA molecule with an KIR receptor | Descriptor: | Beta-2-microglobulin, Killer cell immunoglobulin-like receptor 2DS2, LEU-ASN-PRO-SER-VAL-ALA-ALA-THR-LEU, ... | Authors: | Yang, Y, Yin, L. | Deposit date: | 2021-01-11 | Release date: | 2022-02-02 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Activating receptor KIR2DS2 bound to HLA-C1 reveals the novel recognition features of activating receptor. Immunology, 165, 2022
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7YVJ
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH236 Fab | Descriptor: | Spike glycoprotein, TH236 Fab heavy chain, TH236 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVE
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH027 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH027 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVL
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH272 Fab | Descriptor: | Spike glycoprotein, TH272 Fab heavy chain, TH272 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVI
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH236 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH236 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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8F8Y
| PHF2 (PHD+JMJ) in Complex with VRK1 N-Terminal Peptide | Descriptor: | 1,2-ETHANEDIOL, Lysine-specific demethylase PHF2, SULFATE ION, ... | Authors: | Horton, J.R, Cheng, X. | Deposit date: | 2022-11-22 | Release date: | 2023-01-18 | Last modified: | 2023-02-08 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2. J.Biol.Chem., 299, 2022
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8F8Z
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7WZX
| The structure of a Twitch Radical SAM Dehydrogenase SpeY | Descriptor: | (2~{S},4~{S},6~{R})-2-[(2~{S},3~{R},5~{S},6~{R})-3,5-bis(methylamino)-2,4,6-tris(oxidanyl)cyclohexyl]oxy-6-methyl-4-oxidanyl-oxan-3-one, 4Fe-4S cluster-binding domain-containing protein, GLYCEROL, ... | Authors: | Hou, X.L, Zhou, J.H. | Deposit date: | 2022-02-19 | Release date: | 2022-12-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.980013 Å) | Cite: | Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144, 2022
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7WZV
| The structure of a Twitch Radical SAM Dehydrogenase SpeY | Descriptor: | (1~{S},2~{R},4~{S},5~{R})-2,4-bis(methylamino)-6-[(2~{S},3~{R},4~{S},6~{R})-6-methyl-3,4-bis(oxidanyl)oxan-2-yl]oxy-cyclohexane-1,3,5-triol, 1,2-ETHANEDIOL, 4Fe-4S cluster-binding domain-containing protein, ... | Authors: | Zhou, J.H, Hou, X.L. | Deposit date: | 2022-02-19 | Release date: | 2022-12-28 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.899313 Å) | Cite: | Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144, 2022
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7X0B
| The structure of a Twitch Radical SAM Dehydrogenase SpeY | Descriptor: | 4Fe-4S cluster-binding domain-containing protein, CHLORIDE ION, GLYCEROL, ... | Authors: | Hou, X.L, Zhou, J.H. | Deposit date: | 2022-02-21 | Release date: | 2022-12-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.02027535 Å) | Cite: | Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144, 2022
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7DL0
| The mutant E310G/A314Y of 3,5-DAHDHcca complex with NADPH | Descriptor: | 1,2-ETHANEDIOL, 3,5-diaminohexanoate dehydrogenase, CHLORIDE ION, ... | Authors: | Liu, N, Wu, L, Zhu, D.M, Zhou, J.H. | Deposit date: | 2020-11-25 | Release date: | 2021-09-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of beta-Amino Acids. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DL7
| The wild-type structure of 3,5-DAHDHcca | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,5-diaminohexanoate dehydrogenase, ... | Authors: | Liu, N, Wu, L, Zhu, D.M, Zhou, J.H. | Deposit date: | 2020-11-26 | Release date: | 2021-09-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.30065823 Å) | Cite: | Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of beta-Amino Acids. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DL1
| The mutant E310G/G323S structure of 3,5-DAHDHcca complex with NADPH | Descriptor: | 3,5-diaminohexanoate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Liu, N, Wu, L, Zhu, D.M, Zhou, J.H. | Deposit date: | 2020-11-25 | Release date: | 2021-09-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of beta-Amino Acids. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DL3
| The structure of 3,5-DAHDHcca complex with NADPH | Descriptor: | 3,5-diaminohexanoate dehydrogenase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Liu, N, Wu, L, Zhu, D.M, Zhou, J.H. | Deposit date: | 2020-11-25 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.84606934 Å) | Cite: | Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of beta-Amino Acids. Angew.Chem.Int.Ed.Engl., 60, 2021
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7VOC
| The crystal structure of a Radical SAM Enzyme BlsE involved in the Biosynthesis of Blasticidin S | Descriptor: | (2~{S},3~{S},4~{S},5~{R},6~{R})-6-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4,5-tris(oxidanyl)oxane-2-carboxylic acid, Cytosylglucuronate decarboxylase, GLYCEROL, ... | Authors: | Hou, X.L, Zhou, J.H. | Deposit date: | 2021-10-13 | Release date: | 2022-05-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.62005424 Å) | Cite: | Radical S -Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S. J.Am.Chem.Soc., 144, 2022
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7VOB
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8VXY
| Structure of HamA(E138A,K140A)B-plasmid DNA complex from the Escherichia coli Hachiman defense system | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, HamA, HamB, ... | Authors: | Tuck, O.T, Hu, J.J, Doudna, J.A. | Deposit date: | 2024-02-06 | Release date: | 2024-03-13 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Hachiman is a genome integrity sensor. Biorxiv, 2024
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