7YVL

Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH272 Fab

Summary for 7YVL

• Entry DOI: 10.2210/pdb7yvl/pdb
• EMDB information: 34131
• Descriptor: TH272 Fab heavy chain, TH272 Fab light chain, Spike glycoprotein (3 entities in total)
• Functional Keywords: covid-19, spike glycoprotein, virus, viral protein, antiviral protein-viral protein complex, antiviral protein/viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 167220.48

Authors

Guo, Y.,Zhang, G.,Liang, J.,Liu, F.,Rao, Z. (deposition date: 2022-08-19, release date: 2023-06-28)

• Primary citation: Guo, Y.,Zhang, G.,Yang, Q.,Xie, X.,Lu, Y.,Cheng, X.,Wang, H.,Liang, J.,Tang, J.,Gao, Y.,Shang, H.,Dai, J.,Shi, Y.,Zhou, J.,Zhou, J.,Guo, H.,Yang, H.,Qi, J.,Liu, L.,Ma, S.,Zhang, B.,Huo, Q.,Xie, Y.,Wu, J.,Dong, F.,Zhang, S.,Lou, Z.,Gao, Y.,Song, Z.,Wang, W.,Sun, Z.,Yang, X.,Xiong, D.,Liu, F.,Chen, X.,Zhu, P.,Wang, X.,Cheng, T.,Rao, Z.; Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection.; Nat Commun, 14:3537-3537, 2023; PubMed: 37322000; DOI: 10.1038/s41467-023-39267-x

Experimental method

ELECTRON MICROSCOPY (3.3 Å)