5Z55
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6ULZ
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![BU of 6ulz by Molmil](/molmil-images/mine/6ulz) | Adenylation domain of the initiation module of LgrA mutant P483M | Descriptor: | 3-METHYL-2-OXOBUTANOIC ACID, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, FORMIC ACID, ... | Authors: | Chiche-Lapierre, C, Alonzo, D.A, Schmeing, T.M. | Deposit date: | 2019-10-08 | Release date: | 2020-02-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nat.Chem.Biol., 16, 2020
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7XGY
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![BU of 7xgy by Molmil](/molmil-images/mine/7xgy) | cryo-EM structure of hemoglobin | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Liu, N, Wang, H.W. | Deposit date: | 2022-04-07 | Release date: | 2022-11-09 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Uniform thin ice on ultraflat graphene for high-resolution cryo-EM. Nat.Methods, 20, 2023
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6NYH
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![BU of 6nyh by Molmil](/molmil-images/mine/6nyh) | Structure of human RIPK1 kinase domain in complex with GNE684 | Descriptor: | (5S)-N-[(3S)-7-methoxy-1-methyl-2-oxo-2,3,4,5-tetrahydro-1H-pyrido[3,4-b]azepin-3-yl]-5-phenyl-6,7-dihydro-5H-pyrrolo[1,2-b][1,2,4]triazole-2-carboxamide, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1 | Authors: | Fong, R, Lupardus, P.J. | Deposit date: | 2019-02-11 | Release date: | 2019-05-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases. Cell Death Differ., 27, 2020
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6A0Q
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![BU of 6a0q by Molmil](/molmil-images/mine/6a0q) | The crystal structure of Lpg2622_E64 complex | Descriptor: | Lpg2622, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE | Authors: | Gong, X, Ge, H. | Deposit date: | 2018-06-06 | Release date: | 2018-09-12 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural characterization of the hypothetical protein Lpg2622, a new member of the C1 family peptidases from Legionella pneumophila FEBS Lett., 592, 2018
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8SBG
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8SIJ
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![BU of 8sij by Molmil](/molmil-images/mine/8sij) | Crystal structure of F. varium tryptophanase | Descriptor: | CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, Tryptophanase 1, ... | Authors: | Graboski, A.L, Redinbo, M.R. | Deposit date: | 2023-04-16 | Release date: | 2023-08-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate. Cell Chem Biol, 30, 2023
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8SL7
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![BU of 8sl7 by Molmil](/molmil-images/mine/8sl7) | Butyricicoccus sp. BIOML-A1 tryptophanase complex with (3S) ALG-05 | Descriptor: | (E)-3-[(3S)-3-chloro-2-oxo-2,3-dihydro-1H-indol-3-yl]-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-alanine, Tryptophanase | Authors: | Graboski, A.L, Redinbo, M.R. | Deposit date: | 2023-04-21 | Release date: | 2023-08-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate. Cell Chem Biol, 30, 2023
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4RSC
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![BU of 4rsc by Molmil](/molmil-images/mine/4rsc) | Crystal structure of RPE65 in complex with emixustat and palmitate | Descriptor: | (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol, FE (II) ION, PALMITIC ACID, ... | Authors: | Kiser, P.D, Shi, W, Palczewski, K. | Deposit date: | 2014-11-07 | Release date: | 2015-04-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Catalytic mechanism of a retinoid isomerase essential for vertebrate vision. Nat.Chem.Biol., 11, 2015
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6A0N
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![BU of 6a0n by Molmil](/molmil-images/mine/6a0n) | The crystal structure of apo-Lpg2622 | Descriptor: | Lpg2622 | Authors: | Gong, X, Ge, H. | Deposit date: | 2018-06-05 | Release date: | 2018-09-12 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural characterization of the hypothetical protein Lpg2622, a new member of the C1 family peptidases from Legionella pneumophila FEBS Lett., 592, 2018
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6AJ0
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![BU of 6aj0 by Molmil](/molmil-images/mine/6aj0) | The structure of Enterovirus D68 mature virion | Descriptor: | Capsid protein VP3, Capsid protein VP4, Viral protein 1, ... | Authors: | Zheng, Q.B, Zhu, R, Xu, L.F, He, M.Z, Yan, X.D, Cheng, T, Li, S.W. | Deposit date: | 2018-08-25 | Release date: | 2018-11-07 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization Nat Microbiol, 4, 2019
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6OHT
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![BU of 6oht by Molmil](/molmil-images/mine/6oht) | Structure of EBP and U18666A | Descriptor: | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase, 3beta-(2-Diethylaminoethoxy)androst-5-en-17-one | Authors: | Long, T, Li, X. | Deposit date: | 2019-04-06 | Release date: | 2019-06-19 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition. Nat Commun, 10, 2019
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6ZWJ
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![BU of 6zwj by Molmil](/molmil-images/mine/6zwj) | Neisseria gonorrhoeae transaldolase at 1.35 Angstrom resolution | Descriptor: | CITRIC ACID, GLYCEROL, Transaldolase | Authors: | Rabe von Pappenheim, F, Wensien, M, Sautner, V, Tittmann, K. | Deposit date: | 2020-07-28 | Release date: | 2021-03-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function. Nature, 593, 2021
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6ZWF
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![BU of 6zwf by Molmil](/molmil-images/mine/6zwf) | Neisseria gonorrhoeae transaldolase | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, CITRIC ACID, ... | Authors: | Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K. | Deposit date: | 2020-07-28 | Release date: | 2021-03-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function. Nature, 593, 2021
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6ZWH
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![BU of 6zwh by Molmil](/molmil-images/mine/6zwh) | Neisseria gonorrhoeae transaldolase at 1.5 Angstrom resolution | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ... | Authors: | Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K. | Deposit date: | 2020-07-28 | Release date: | 2021-03-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function. Nature, 593, 2021
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6ZX4
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![BU of 6zx4 by Molmil](/molmil-images/mine/6zx4) | Neisseria gonorrhoeae transaldolase | Descriptor: | CITRIC ACID, GLYCEROL, Transaldolase | Authors: | Sautner, V, Rabe von Pappenheim, F, Wensien, M, Tittmann, K. | Deposit date: | 2020-07-29 | Release date: | 2021-03-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function. Nature, 593, 2021
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6LIX
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![BU of 6lix by Molmil](/molmil-images/mine/6lix) | CRL Protein of Arabidopsis | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Chromophore lyase CRL, chloroplastic | Authors: | Wang, F.F, Guan, K.L, Sun, P.K, Xing, W.M. | Deposit date: | 2019-12-13 | Release date: | 2020-09-16 | Last modified: | 2020-12-02 | Method: | X-RAY DIFFRACTION (2.385 Å) | Cite: | The Arabidopsis CRUMPLED LEAF protein, a homolog of the cyanobacterial bilin lyase, retains the bilin-binding pocket for a yet unknown function. Plant J., 104, 2020
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8UWA
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![BU of 8uwa by Molmil](/molmil-images/mine/8uwa) | VH1-18 QxxV class antibody 09-1B12 bound to A/Perth/16/2009 H3N2 hemagglutinin | Descriptor: | 09-1B12 heavy chain, 09-1B12 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Maurer, D.P. | Deposit date: | 2023-11-06 | Release date: | 2024-05-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (4.02 Å) | Cite: | Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses. Immunity, 57, 2024
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6AJ9
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![BU of 6aj9 by Molmil](/molmil-images/mine/6aj9) | The structure of Enterovirus D68 mature virion in complex with Fab 15C5 and 11G1 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Zheng, Q.B, Zhu, R, Xu, L.F, He, M.Z, Yan, X.D, Cheng, T, Li, S.W. | Deposit date: | 2018-08-27 | Release date: | 2018-11-07 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization Nat Microbiol, 4, 2019
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8T1U
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![BU of 8t1u by Molmil](/molmil-images/mine/8t1u) | Crystal structure of the DRM2-CTA DNA complex | Descriptor: | DNA (5'-D(P*AP*TP*TP*AP*TP*TP*AP*AP*TP*(C49)P*TP*AP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*AP*TP*TP*TP*AP*GP*AP*TP*TP*AP*AP*TP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ... | Authors: | Chen, J, Lu, J, Song, J. | Deposit date: | 2023-06-03 | Release date: | 2023-11-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | DNA conformational dynamics in the context-dependent non-CG CHH methylation by plant methyltransferase DRM2. J.Biol.Chem., 299, 2023
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8VC8
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6ULY
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![BU of 6uly by Molmil](/molmil-images/mine/6uly) | Adenylation domain of a keto acid-selecting NRPS module bound to keto acyl adenylate space group P212121 | Descriptor: | 5'-O-{(S)-hydroxy[(4-methyl-2-oxopentanoyl)oxy]phosphoryl}adenosine, Amino acid adenylation domain-containing protein, GLYCEROL, ... | Authors: | Alonzo, D.A, Chiche-Lapierre, C, Schmeing, T.M. | Deposit date: | 2019-10-08 | Release date: | 2020-02-19 | Last modified: | 2020-05-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nat.Chem.Biol., 16, 2020
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6OHU
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![BU of 6ohu by Molmil](/molmil-images/mine/6ohu) | Structure of EBP and tamoxifen | Descriptor: | (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE, 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | Authors: | Long, T, Li, X. | Deposit date: | 2019-04-06 | Release date: | 2019-06-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.526 Å) | Cite: | Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition. Nat Commun, 10, 2019
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7PQV
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![BU of 7pqv by Molmil](/molmil-images/mine/7pqv) | MEK1 IN COMPLEX WITH COMPOUND 7 | Descriptor: | 8-(2-chloranyl-4-methoxy-phenyl)-7-fluoranyl-1-piperidin-4-yl-imidazo[4,5-c]quinoline, CALCIUM ION, Dual specificity mitogen-activated protein kinase kinase 1, ... | Authors: | Moebitz, H. | Deposit date: | 2021-09-20 | Release date: | 2022-03-16 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Discovery of MAP855, an Efficacious and Selective MEK1/2 Inhibitor with an ATP-Competitive Mode of Action. J.Med.Chem., 65, 2022
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6LIY
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![BU of 6liy by Molmil](/molmil-images/mine/6liy) | SeMet CRL Protein of Arabidopsis | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Chromophore lyase CRL, chloroplastic | Authors: | Wang, F.F, Guan, K.L, Sun, P.K, Xing, W.M. | Deposit date: | 2019-12-13 | Release date: | 2020-09-16 | Last modified: | 2020-12-02 | Method: | X-RAY DIFFRACTION (1.761 Å) | Cite: | The Arabidopsis CRUMPLED LEAF protein, a homolog of the cyanobacterial bilin lyase, retains the bilin-binding pocket for a yet unknown function. Plant J., 104, 2020
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