8SIJ
Crystal structure of F. varium tryptophanase
Summary for 8SIJ
| Entry DOI | 10.2210/pdb8sij/pdb |
| Descriptor | Tryptophanase 1, PYRIDOXAL-5'-PHOSPHATE, CHLORIDE ION, ... (5 entities in total) |
| Functional Keywords | plp-dependent enzyme, tryptophan indole-lyase, tryptophanase, lyase |
| Biological source | Fusobacterium varium |
| Total number of polymer chains | 2 |
| Total formula weight | 109788.48 |
| Authors | Graboski, A.L.,Redinbo, M.R. (deposition date: 2023-04-16, release date: 2023-08-23, Last modification date: 2023-11-29) |
| Primary citation | Graboski, A.L.,Kowalewski, M.E.,Simpson, J.B.,Cao, X.,Ha, M.,Zhang, J.,Walton, W.G.,Flaherty, D.P.,Redinbo, M.R. Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate. Cell Chem Biol, 30:1402-1413.e7, 2023 Cited by PubMed: 37633277DOI: 10.1016/j.chembiol.2023.07.015 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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