8SBG
Crystal structure of B. theta tryptophanase in holo form
Summary for 8SBG
Entry DOI | 10.2210/pdb8sbg/pdb |
Descriptor | Tryptophanase, PYRIDOXAL-5'-PHOSPHATE (3 entities in total) |
Functional Keywords | plp-dependent enzyme, tryptophanase, tryptophan-indole lyase, lyase |
Biological source | Bacteroides thetaiotaomicron |
Total number of polymer chains | 1 |
Total formula weight | 54833.82 |
Authors | Graboski, A.L.,Redinbo, M.R. (deposition date: 2023-04-03, release date: 2023-08-23, Last modification date: 2023-11-29) |
Primary citation | Graboski, A.L.,Kowalewski, M.E.,Simpson, J.B.,Cao, X.,Ha, M.,Zhang, J.,Walton, W.G.,Flaherty, D.P.,Redinbo, M.R. Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate. Cell Chem Biol, 30:1402-1413.e7, 2023 Cited by PubMed: 37633277DOI: 10.1016/j.chembiol.2023.07.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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