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4RSC

Crystal structure of RPE65 in complex with emixustat and palmitate

Summary for 4RSC
Entry DOI10.2210/pdb4rsc/pdb
Related3FSN 4F2Z 4RSE
DescriptorRetinoid isomerohydrolase, FE (II) ION, PALMITIC ACID, ... (5 entities in total)
Functional Keywords7-bladed beta propeller, monotopic membrane protein, non-heme iron enzyme, retinoid isomerase, smooth endoplasmic reticulum, isomerase
Biological sourceBos taurus (bovine,cow,domestic cattle,domestic cow)
Cellular locationCytoplasm: Q28175
Total number of polymer chains2
Total formula weight123231.68
Authors
Kiser, P.D.,Shi, W.,Palczewski, K. (deposition date: 2014-11-07, release date: 2015-04-15, Last modification date: 2023-09-20)
Primary citationKiser, P.D.,Zhang, J.,Badiee, M.,Li, Q.,Shi, W.,Sui, X.,Golczak, M.,Tochtrop, G.P.,Palczewski, K.
Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Nat.Chem.Biol., 11:409-415, 2015
Cited by
PubMed: 25894083
DOI: 10.1038/nchembio.1799
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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