6ULY

Adenylation domain of a keto acid-selecting NRPS module bound to keto acyl adenylate space group P212121

Summary for 6ULY

Entry DOI	10.2210/pdb6uly/pdb
Descriptor	Amino acid adenylation domain-containing protein, 5'-O-{(S)-hydroxy[(4-methyl-2-oxopentanoyl)oxy]phosphoryl}adenosine, SULFATE ION, ... (5 entities in total)
Functional Keywords	nrps, nonribosomal peptide synthetase, non-ribosomal peptide synthetase, adenylation, adenylation domain, depsipeptide, cereulide, valinomycin, natural product, adenylate, keto acid, ketoacid, biosynthetic protein
Biological source	Bacillus stratosphericus LAMA 585
Total number of polymer chains	2
Total formula weight	130900.82
Authors	Alonzo, D.A.,Chiche-Lapierre, C.,Schmeing, T.M. (deposition date: 2019-10-08, release date: 2020-02-19, Last modification date: 2020-05-06)
Primary citation	Alonzo, D.A.,Chiche-Lapierre, C.,Tarry, M.J.,Wang, J.,Schmeing, T.M. Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nat.Chem.Biol., 16:493-496, 2020 Cited by PubMed: 32066969 DOI: 10.1038/s41589-020-0481-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation