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7U5B
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BU of 7u5b by Molmil
Structure of Human KLK5 bound to anti-KLK5 Fab
Descriptor: Kallikrein-5, SULFATE ION, anti-KLK5 Fab Heavy Chain, ...
Authors:Yin, J, Sudhamsu, J.
Deposit date:2022-03-02
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.371 Å)
Cite:Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis.
Sci Transl Med, 14, 2022
2QSS
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BU of 2qss by Molmil
Bovine hemoglobin at pH 6.3
Descriptor: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
Authors:Aranda IV, R, Richards, M.P, Phillips Jr, G.N.
Deposit date:2007-07-31
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
2QSP
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BU of 2qsp by Molmil
Bovine Hemoglobin at pH 5.7
Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
Authors:Aranda IV, R, Richards, M.P, Phillips Jr, G.N.
Deposit date:2007-07-31
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
7YTJ
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BU of 7ytj by Molmil
Cryo-EM structure of VTC complex
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, INOSITOL HEXAKISPHOSPHATE, PHOSPHATE ION, ...
Authors:Guan, Z.Y, Chen, J, Liu, R.W, Chen, Y.K, Xing, Q, Du, Z.M, Liu, Z.
Deposit date:2022-08-15
Release date:2023-02-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex.
Nat Commun, 14, 2023
8AG1
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BU of 8ag1 by Molmil
Crystal structure of a novel OX40 antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Novel OX40 antibody heavy chain, Novel OX40 antibody light chain, ...
Authors:Gao, H, Zhou, A.
Deposit date:2022-07-19
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.303 Å)
Cite:Structural Basis of a Novel Agonistic Anti-OX40 Antibody.
Biomolecules, 12, 2022
6M6F
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BU of 6m6f by Molmil
Solution structure of disulfide bond mutaion of the core domain of Fibroblast growth factor 21 (FGF21)
Descriptor: Fibroblast growth factor 21
Authors:Zhu, L, Zhao, H, Wang, J.
Deposit date:2020-03-14
Release date:2021-01-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Dynamic folding modulation generates FGF21 variant against diabetes.
Embo Rep., 22, 2021
6M6E
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BU of 6m6e by Molmil
Solution structure of the core domain of Fibroblast growth factor 21 (FGF21)
Descriptor: Fibroblast growth factor 21
Authors:Zhu, L, Zhao, H, Wang, J.
Deposit date:2020-03-14
Release date:2021-01-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Dynamic folding modulation generates FGF21 variant against diabetes.
Embo Rep., 22, 2021
3CUE
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BU of 3cue by Molmil
Crystal structure of a TRAPP subassembly activating the Rab Ypt1p
Descriptor: GTP-binding protein YPT1, PALMITIC ACID, Transport protein particle 18 kDa subunit, ...
Authors:Cai, Y, Reinisch, K.M.
Deposit date:2008-04-16
Release date:2008-07-08
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes.
Cell(Cambridge,Mass.), 133, 2008
5INW
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BU of 5inw by Molmil
Structure of reaction loop cleaved lamprey angiotensinogen
Descriptor: C-terminal peptide of Putative angiotensinogen, Putative angiotensinogen, SULFATE ION
Authors:Wei, H, Zhou, A.
Deposit date:2016-03-08
Release date:2016-10-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism
J.Biol.Chem., 291, 2016
7LT2
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BU of 7lt2 by Molmil
Structure of a dsRNA-sensing cGAS-like receptor from the beetle Tribolium castaneum
Descriptor: MANGANESE (II) ION, Mab-21 domain-containing protein
Authors:Slavik, K.M, Morehouse, B.R, Kranzusch, P.J.
Deposit date:2021-02-18
Release date:2021-07-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
7LT1
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BU of 7lt1 by Molmil
Structure of the cGAS-like receptor human MB21D2
Descriptor: Protein MB21D2, SULFATE ION
Authors:Morehouse, B.R, Slavik, K.M, Kranzusch, P.J.
Deposit date:2021-02-18
Release date:2021-07-21
Last modified:2021-09-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
7MWY
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BU of 7mwy by Molmil
Structure of the drosophila STING cyclic dinucleotide binding domain
Descriptor: STING
Authors:Slavik, K.M, Ragucci, A.E, Kranzusch, P.J.
Deposit date:2021-05-17
Release date:2021-07-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
7MWZ
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BU of 7mwz by Molmil
Structure of drosophila STING in complex with 3'2'-cGAMP
Descriptor: 3'2'-cGAMP, STING
Authors:Slavik, K.M, Ragucci, A.E, Kranzusch, P.J.
Deposit date:2021-05-17
Release date:2021-07-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
7SEG
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BU of 7seg by Molmil
Crystal structure of the complex of CD16A bound by an anti-CD16A Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Kiefer, J.R, Wallweber, H.A, Polson, A.G.
Deposit date:2021-09-30
Release date:2021-11-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.156 Å)
Cite:A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma.
Leukemia, 36, 2022
5UD9
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BU of 5ud9 by Molmil
Crystal structure of 354BG18 Fab
Descriptor: Fab heavy chain, Light chain
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2016-12-23
Release date:2017-02-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
5UEL
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BU of 5uel by Molmil
Crystal structure of 354NC102 Fab
Descriptor: 354NC102 Fab Heavy Chain, 354NC102 Fab Light Chain, SULFATE ION
Authors:Sievers, S.A, Gristick, H.B, Bjorkman, P.J.
Deposit date:2017-01-02
Release date:2017-02-01
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
5UEM
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BU of 5uem by Molmil
Crystal structure of 354NC37 Fab in complex with HIV-1 clade AE strain 93TH057 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 354NC37 Fab Heavy Chain, ...
Authors:Sievers, S.A, Gristick, H.B, Bjorkman, P.J.
Deposit date:2017-01-02
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
5UUT
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BU of 5uut by Molmil
N-myristoyltransferase 1 (NMT) bound to myristoyl-CoA
Descriptor: CITRIC ACID, Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA
Authors:Goodwin, O, Pegan, S.
Deposit date:2017-02-17
Release date:2018-01-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.252 Å)
Cite:Blocking Myristoylation of Src Inhibits Its Kinase Activity and Suppresses Prostate Cancer Progression.
Cancer Res., 77, 2017
2R1H
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BU of 2r1h by Molmil
met-Trout IV hemoglobin at pH 6.3
Descriptor: 1,2-ETHANEDIOL, Hemoglobin subunit alpha-4, Hemoglobin subunit beta-4, ...
Authors:Aranda IV, R, Worley, C.E, Richards, M.P, Phillips Jr, G.N.
Deposit date:2007-08-22
Release date:2008-09-02
Last modified:2013-01-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
7V6Z
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BU of 7v6z by Molmil
Cryo-EM structure of Patched1 (V1084A mutant) in lipid nanodisc, 3.64 angstrom (reprocessed with the dataset of 7dzp)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
Authors:Luo, Y, Zhao, Y, Qu, Q, Li, D.
Deposit date:2021-08-20
Release date:2021-09-22
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Cryo-EM study of patched in lipid nanodisc suggests a structural basis for its clustering in caveolae.
Structure, 29, 2021
7V6Y
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BU of 7v6y by Molmil
Cryo-EM structure of Patched in lipid nanodisc - the wildtype, 3.5 angstrom (re-processed with dataset of 7dzq)
Descriptor: (2S)-2-azanyl-3-[[(2S)-3-butanoyloxy-2-dec-9-enoyloxy-propoxy]-oxidanyl-phosphoryl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Luo, Y, Zhao, Y, Qu, Q, Li, D.
Deposit date:2021-08-20
Release date:2021-09-22
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM study of patched in lipid nanodisc suggests a structural basis for its clustering in caveolae.
Structure, 29, 2021
7YK4
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BU of 7yk4 by Molmil
ox40-antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor receptor superfamily member 4, antibody-H, ...
Authors:Zhou, A.
Deposit date:2022-07-21
Release date:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of a Novel Agonistic Anti-OX40 Antibody.
Biomolecules, 12, 2022
5XXY
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BU of 5xxy by Molmil
Crystal structure of PD-L1 complexed with atezolizumab fab at 2.9A
Descriptor: Programmed cell death 1 ligand 1, heavy chain of atezolizumab fab, light chain of atezolizumab fab
Authors:Zhou, A, Zhang, F.
Deposit date:2017-07-05
Release date:2017-09-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of the therapeutic anti-PD-L1 antibody atezolizumab.
Oncotarget, 8, 2017
8JRU
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BU of 8jru by Molmil
Cryo-EM structure of the glucagon receptor bound to beta-arrestin 1 in ligand-free state
Descriptor: Beta-arrestin 1 and single-chain fragment variable 30 (scFv30), HA signal peptide,HPC4 purification tag,Glucagon receptor,C-terminal tail of Vasopressin V2 receptor, Nanobody 32, ...
Authors:Chen, K, Zhang, C, Lin, S, Zhao, Q, Wu, B.
Deposit date:2023-06-17
Release date:2023-08-16
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Tail engagement of arrestin at the glucagon receptor.
Nature, 620, 2023
8JRV
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BU of 8jrv by Molmil
Cryo-EM structure of the glucagon receptor bound to glucagon and beta-arrestin 1
Descriptor: Beta-arrestin 1 and single-chain fragment variable 30 (scFv30), Glucagon, HA signal peptide,HPC4 purification tag,Glucagon receptor,C-terminal tail of Vasopressin V2 receptor, ...
Authors:Chen, K, Zhang, C, Lin, S, Zhao, Q, Wu, B.
Deposit date:2023-06-17
Release date:2023-08-16
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Tail engagement of arrestin at the glucagon receptor.
Nature, 620, 2023

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