8JRU

Cryo-EM structure of the glucagon receptor bound to beta-arrestin 1 in ligand-free state

Summary for 8JRU

• Entry DOI: 10.2210/pdb8jru/pdb
• EMDB information: 36606
• Descriptor: HA signal peptide,HPC4 purification tag,Glucagon receptor,C-terminal tail of Vasopressin V2 receptor, Beta-arrestin 1 and single-chain fragment variable 30 (scFv30), Nanobody 32, ... (4 entities in total)
• Functional Keywords: complex structure, glucagon receptor, beta-arrestin 1, ligand-free, membrane protein
• Biological source: Influenza A virus (strain A/Victoria/3/1975 H3N2); More
• Total number of polymer chains: 5
• Total formula weight: 276442.79

Authors

Chen, K.,Zhang, C.,Lin, S.,Zhao, Q.,Wu, B. (deposition date: 2023-06-17, release date: 2023-08-16, Last modification date: 2023-09-13)

• Primary citation: Chen, K.,Zhang, C.,Lin, S.,Yan, X.,Cai, H.,Yi, C.,Ma, L.,Chu, X.,Liu, Y.,Zhu, Y.,Han, S.,Zhao, Q.,Wu, B.; Tail engagement of arrestin at the glucagon receptor.; Nature, 620:904-910, 2023; PubMed: 37558880; DOI: 10.1038/s41586-023-06420-x

Experimental method

ELECTRON MICROSCOPY (3.5 Å)