5UUT
N-myristoyltransferase 1 (NMT) bound to myristoyl-CoA
Summary for 5UUT
Entry DOI | 10.2210/pdb5uut/pdb |
Descriptor | Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA, CITRIC ACID, ... (4 entities in total) |
Functional Keywords | myristoylation, myristoyl-coa, cancer, co/post-translational modification, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 93246.72 |
Authors | Goodwin, O.,Pegan, S. (deposition date: 2017-02-17, release date: 2018-01-17, Last modification date: 2024-03-06) |
Primary citation | Kim, S.,Alsaidan, O.A.,Goodwin, O.,Li, Q.,Sulejmani, E.,Han, Z.,Bai, A.,Albers, T.,Beharry, Z.,Zheng, Y.G.,Norris, J.S.,Szulc, Z.M.,Bielawska, A.,Lebedyeva, I.,Pegan, S.D.,Cai, H. Blocking Myristoylation of Src Inhibits Its Kinase Activity and Suppresses Prostate Cancer Progression. Cancer Res., 77:6950-6962, 2017 Cited by PubMed: 29038344DOI: 10.1158/0008-5472.CAN-17-0981 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.252 Å) |
Structure validation
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