8JRV
Cryo-EM structure of the glucagon receptor bound to glucagon and beta-arrestin 1
Summary for 8JRV
Entry DOI | 10.2210/pdb8jrv/pdb |
EMDB information | 36607 |
Descriptor | HA signal peptide,HPC4 purification tag,Glucagon receptor,C-terminal tail of Vasopressin V2 receptor, Glucagon, Beta-arrestin 1 and single-chain fragment variable 30 (scFv30), ... (5 entities in total) |
Functional Keywords | complex structure, glucagon receptor, beta-arrestin 1, glucagon, membrane protein |
Biological source | Influenza A virus (strain A/Victoria/3/1975 H3N2) More |
Total number of polymer chains | 6 |
Total formula weight | 279785.44 |
Authors | |
Primary citation | Chen, K.,Zhang, C.,Lin, S.,Yan, X.,Cai, H.,Yi, C.,Ma, L.,Chu, X.,Liu, Y.,Zhu, Y.,Han, S.,Zhao, Q.,Wu, B. Tail engagement of arrestin at the glucagon receptor. Nature, 620:904-910, 2023 Cited by PubMed: 37558880DOI: 10.1038/s41586-023-06420-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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