tRNA tranlocation on the 70S ribosome: the pre-translocational translocation intermediate TI(PRE)

This is a large structure.

Summary for 4V5M

Related1IBK 1IBL 2UUC 2WDK 2J02 1J5E 2WRQ 1HNX 2J00 2B9O 2X9T 2UUB 2WH3 1VOV 1EMI 2XQD 2V46 1PNX 2EFG 2VQF 2WH1 1N32 1ELO 2WRN 2JL5 2F4V 1TWT 1QZC 2UXD 1FKA 1FJG 1N36 2UXC 1HNW 1L1U 1HR0 2V48 2B64 1XMQ 1DAR 2B9M 1PN8 2WDG 1XNR 1DV4 1HNZ 1RSS 2WDH 1JGQ 1I94 1I96 2UU9 1PN7 1EG0 1IBM 2UXB 2VQE 1G1X 2UUA 1I95 1XNQ 2XFZ 1QD7 1GIX 1EFG 1JGO 1JGP 2XG1 2X9R 1N34 1N33 1PNS 2JL7 1YL4 2WDM 1XMO 1I97
Integrates2XSY 2XTG
EMDB information1798
Descriptor16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... (59 entities in total)
Functional Keywordsribosome, translation, elongation cycle
Cellular locationCytoplasm Q5SHN5
Total number of polymer chains57
Total molecular weight2311295.79
Primary citation
Ratje, A.H.,Loerke, J.,Mikolajka, A.,Brunner, M.,Hildebrand, P.W.,Starosta, A.L.,Donhofer, A.,Connell, S.R.,Fucini, P.,Mielke, T.,Whitford, P.C.,Onuchic, J.N.,Yu, Y.,Sanbonmatsu, K.Y.,Hartmann, R.K.,Penczek, P.A.,Wilson, D.N.,Spahn, C.M.T.
Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468:713-, 2010
PubMed: 21124459 (PDB entries with the same primary citation)
DOI: 10.1038/NATURE09547
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone4711.9%13.6%0.44MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 4v5m
no rotation
Molmil generated image of 4v5m
rotated about x axis by 90°
Molmil generated image of 4v5m
rotated about y axis by 90°