4V5J

Structure of the 70S ribosome bound to Release factor 2 and a substrate analog provides insights into catalysis of peptide release

This is a large structure.

Summary for 4V5J

Related1IBK 1IBL 2UUC 2WDK 2J02 1J5E 2WRQ 2J00 1HNX 2B9O 2WH3 2UUB 1VOV 1EMI 1PNX 2V46 2VQF 2WH1 1N32 2WRN 2F4V 1TWT 1QZC 2UXD 1FKA 1FJG 1N36 2UXC 1HNW 1L1U 1HR0 2V48 2B64 1XMQ 2B9M 1PN8 2WDG 1XNR 1HNZ 1DV4 1RSS 2WDH 1JGQ 1I94 1I96 2UU9 1PN7 1EG0 1IBM 2UXB 2VQE 1G1X 1I95 2UUA 1XNQ 1QD7 1GIX 1JGO 1JGP 1N34 1N33 1PNS 1YL4 2WDM 1XMO 1I97
Integrates2X9R 2X9S 2X9T 2X9U
Descriptor16S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... (61 entities in total)
Functional Keywordsribosomal protein, ribonucleoprotein, trna-binding, rrna-binding, metal-binding, ribosome, zinc-finger, translation
Biological sourceTHERMUS THERMOPHILUS
More
Cellular locationCytoplasm  Q5SM01
Total number of polymer chains118
Total molecular weight4650645.7
Authors
Jin, H.,Kelley, A.C.,Loakes, D.,Ramakrishnan, V. (deposition date: 2010-03-24, release date: 2014-07-09, Last modification date: 2018-04-18)
Primary citation
Jin, H.,Kelley, A.C.,Loakes, D.,Ramakrishnan, V.
Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release.
Proc. Natl. Acad. Sci. U.S.A., 107:8593-8598, 2010
PubMed: 20421507 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1003995107
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.1 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.2653511.2%10.4%6.9%0.56MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4v5j
no rotation
Molmil generated image of 4v5j
rotated about x axis by 90°
Molmil generated image of 4v5j
rotated about y axis by 90°