4AA6

The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation

Summary for 4AA6

Related2YAT 2YJA 1XP1 1QKT 1R5K 1ZKY 2BJ4 1HCP 1AKF 1HCQ 1A52 1QKU 1XP6 1G50 1PCG 2B1V 2JF9 1UOM 1YIM 2AYR 1YIN 3ERT 1ERR 1X7R 3ERD 1L2I 2FAI 1XP9 1GWR 2JFA 1SJ0 1GWQ 1XPC 1X7E 1XQC 1ERE
DescriptorESTROGEN RECEPTOR, 5'-D(*CP*TP*AP*AP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP *CP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*GP*TP*CP*AP*CP*TP*GP*TP*GP*AP *CP*TP*TP*A)-3', ... (5 entities in total)
Functional Keywordstranscription-dna complex, estrogen, estrogen receptor, transcription/dna
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationIsoform 1: Nucleus. Isoform 3: Nucleus P03372
Total number of polymer chains8
Total molecular weight55595.84
Authors
Schwabe, J.W.,Chapman, L.,Rhodes, D. (deposition date: 2011-11-30, release date: 2011-12-14)
Primary citation
Schwabe, J.W.,Chapman, L.,Rhodes, D.
The Oestrogen Receptor Recognizes an Imperfectly Palindromic Response Element Through an Alternative Side-Chain Conformation.
Structure, 3:201-, 1995
PubMed: 7735836 (PDB entries with the same primary citation)
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers71.2%1.4%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4aa6
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Molmil generated image of 4aa6
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Molmil generated image of 4aa6
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More Biological unit images

Molmil generated image of 4aa6
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Molmil generated image of 4aa6
rotated about x axis by 90°
Molmil generated image of 4aa6
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (4aa6.pdb2.gz [45.69 KB])
Coordinate files for Biological unit (4aa6.pdb1.gz [48.18 KB])