4AA6
The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0043565 | molecular_function | sequence-specific DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0043565 | molecular_function | sequence-specific DNA binding |
| E | 0003700 | molecular_function | DNA-binding transcription factor activity |
| E | 0006355 | biological_process | regulation of DNA-templated transcription |
| E | 0008270 | molecular_function | zinc ion binding |
| E | 0043565 | molecular_function | sequence-specific DNA binding |
| F | 0003700 | molecular_function | DNA-binding transcription factor activity |
| F | 0006355 | biological_process | regulation of DNA-templated transcription |
| F | 0008270 | molecular_function | zinc ion binding |
| F | 0043565 | molecular_function | sequence-specific DNA binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 253 |
| Chain | Residue |
| A | CYS185 |
| A | CYS188 |
| A | CYS202 |
| A | CYS205 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 254 |
| Chain | Residue |
| A | CYS221 |
| A | CYS227 |
| A | CYS237 |
| A | CYS240 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 253 |
| Chain | Residue |
| B | CYS188 |
| B | CYS202 |
| B | CYS205 |
| B | CYS185 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 254 |
| Chain | Residue |
| B | CYS221 |
| B | CYS227 |
| B | CYS237 |
| B | CYS240 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN E 253 |
| Chain | Residue |
| E | CYS185 |
| E | CYS188 |
| E | CYS202 |
| E | CYS205 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN E 254 |
| Chain | Residue |
| E | CYS221 |
| E | CYS227 |
| E | CYS237 |
| E | CYS240 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN F 253 |
| Chain | Residue |
| F | CYS185 |
| F | CYS188 |
| F | CYS202 |
| F | CYS205 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN F 254 |
| Chain | Residue |
| F | CYS221 |
| F | CYS227 |
| F | CYS237 |
| F | CYS240 |
Functional Information from PROSITE/UniProt
| site_id | PS00031 |
| Number of Residues | 27 |
| Details | NUCLEAR_REC_DBD_1 Nuclear hormones receptors DNA-binding region signature. CavCn.Dyasgy.HYgvwsCegCkaFFkR |
| Chain | Residue | Details |
| A | CYS185-ARG211 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 152 |
| Details | Zinc finger: {"description":"NR C4-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00407","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
