2YJA

Stapled Peptides binding to Estrogen Receptor alpha.

Summary for 2YJA

Entry DOI	10.2210/pdb2yja/pdb
Related	1A52 1AKF 1ERE 1ERR 1G50 1GWQ 1GWR 1HCP 1HCQ 1L2I 1PCG 1QKT 1QKU 1R5K 1SJ0 1UOM 1X7E 1X7R 1XP1 1XP6 1XP9 1XPC 1XQC 1YIM 1YIN 1ZKY 2AYR 2B1V 2BJ4 2FAI 2JF9 2JFA 2LDA 2LDC 2LDD 2YAT 2YJD 3ERD 3ERT
Descriptor	STAPLED PEPTIDE, ESTROGEN RECEPTOR, ESTRADIOL, ... (4 entities in total)
Functional Keywords	hormone receptor-peptide complex, hormone receptor/peptide
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Isoform 1: Nucleus. Isoform 3: Nucleus: P03372
Total number of polymer chains	2
Total formula weight	30780.33
Authors	Phillips, C.,Roberts, L.R.,Schade, M.,Bazin, R.,Bent, A.,Davies, N.L.,Irving, S.L.,Moore, R.,Pannifer, A.D.,Brown, D.G.,Pickford, A.R.,Scott, A.,Xu, B. (deposition date: 2011-05-19, release date: 2011-08-03)
Primary citation	Phillips, C.,Roberts, L.R.,Schade, M.,Bazin, R.,Bent, A.,Davies, N.L.,Moore, R.,Pannifer, A.D.,Pickford, A.R.,Prior, S.H.,Read, C.M.,Scott, A.,Brown, D.G.,Xu, B.,Irving, S.L. Design and Structure of Stapled Peptides Binding to Estrogen Receptors. J.Am.Chem.Soc., 133:9696-, 2011 Cited by PubMed: 21612236 DOI: 10.1021/JA202946K PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation