2YHD
Human androgen receptor in complex with AF2 small molecule inhibitor
Summary for 2YHD
Entry DOI | 10.2210/pdb2yhd/pdb |
Related | 1E3G 1GS4 1T5Z 1T63 1T65 1XJ7 1XOW 1XQ3 1Z95 2AM9 2AMA 2AMB 2AO6 2AX6 2AX7 2AX8 2AX9 2AXA |
Descriptor | ANDROGEN RECEPTOR, SULFATE ION, TESTOSTERONE, ... (5 entities in total) |
Functional Keywords | transcription, activation function 2 site (af2), small molecule inhibitor |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus: P10275 |
Total number of polymer chains | 1 |
Total formula weight | 29708.87 |
Authors | AxerioCilies, P.,Lack, N.A.,ShashiNayana, M.R.,Chan, K.H.,Yeung, A.,LeBlanc, E.,Guns, E.,Rennie, P.,Cherkasov, A. (deposition date: 2011-04-28, release date: 2011-09-21, Last modification date: 2023-12-20) |
Primary citation | Axerio-Cilies, P.,Lack, N.A.,Nayana, M.R.,Chan, K.H.,Yeung, A.,Leblanc, E.,Guns, E.S.,Rennie, P.S.,Cherkasov, A. Inhibitors of Androgen Receptor Activation Function-2 (Af2) Site Identified Through Virtual Screening. J.Med.Chem., 54:6197-, 2011 Cited by PubMed: 21846139DOI: 10.1021/JM200532B PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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