2AXA

Crystal Structure Of The Androgen Receptor Ligand Binding Domain In Complex With S-1

Summary for 2AXA

Entry DOI	10.2210/pdb2axa/pdb
Related	2AX6 2AX7 2AX8 2AX9
Descriptor	Androgen receptor, S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE (3 entities in total)
Functional Keywords	transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus : P10275
Total number of polymer chains	1
Total formula weight	30271.25
Authors	Bohl, C.E.,Miller, D.D.,Chen, J.,Bell, C.E.,Dalton, J.T. (deposition date: 2005-09-03, release date: 2005-09-20, Last modification date: 2023-08-23)
Primary citation	Bohl, C.E.,Miller, D.D.,Chen, J.,Bell, C.E.,Dalton, J.T. Structural Basis for Accommodation of Nonsteroidal Ligands in the Androgen Receptor J.Biol.Chem., 280:37747-37754, 2005 Cited by PubMed: 16129672 DOI: 10.1074/jbc.M507464200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation