2AX8
Crystal Structure Of The Androgen Receptor Ligand Binding Domain W741L Mutant In Complex With S-1
Summary for 2AX8
Entry DOI | 10.2210/pdb2ax8/pdb |
Related | 2ax6 2ax7 2ax9 2axa |
Descriptor | Androgen receptor, S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE (3 entities in total) |
Functional Keywords | transcription |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : P10275 |
Total number of polymer chains | 1 |
Total formula weight | 30198.19 |
Authors | Bohl, C.E.,Miller, D.D.,Chen, J.,Bell, C.E.,Dalton, J.T. (deposition date: 2005-09-03, release date: 2005-09-20, Last modification date: 2023-08-23) |
Primary citation | Bohl, C.E.,Miller, D.D.,Chen, J.,Bell, C.E.,Dalton, J.T. Structural Basis for Accommodation of Nonsteroidal Ligands in the Androgen Receptor J.Biol.Chem., 280:37747-37754, 2005 Cited by PubMed: 16129672DOI: 10.1074/jbc.M507464200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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