2AX8
Crystal Structure Of The Androgen Receptor Ligand Binding Domain W741L Mutant In Complex With S-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 256 | 29795.9 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (human) | |
| 2 | B (A) | S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE | non-polymer | 402.3 | 1 | Chemie (FHM) | |||
| 3 | C (A) | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
A: 664 - 919 (UniProt: P10275)
| PDB | External Database | Details |
|---|---|---|
| Leu 741 | Trp 740 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29795.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 402.3 | |
| All* | Total formula weight | 30198.2 |
