2Y1N
Structure of c-Cbl-ZAP-70 peptide complex
Summary for 2Y1N
Entry DOI | 10.2210/pdb2y1n/pdb |
Related | 1B47 1FBV 1M61 1U59 1YVH 2CBL 2Y1M 4A49 4A4B 4A4C |
Descriptor | E3 UBIQUITIN-PROTEIN LIGASE, TYROSINE-PROTEIN KINASE ZAP-70 ZAP-70,70 KDA ZETA-ASSOCIATED PROTEIN, SYK-RELATED TYROSINE KINASE, ZINC ION, ... (5 entities in total) |
Functional Keywords | ligase-transferase complex, ubiquitin ring e3 ligase, ligase/transferase |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasm: P22681 P43403 |
Total number of polymer chains | 4 |
Total formula weight | 92887.73 |
Authors | Dou, H.,Sibbet, G.J.,Huang, D.T. (deposition date: 2010-12-08, release date: 2012-01-18, Last modification date: 2023-12-20) |
Primary citation | Dou, H.,Buetow, L.,Hock, A.,Sibbet, G.J.,Vousden, K.H.,Huang, D.T. Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl. Nat.Struct.Mol.Biol., 19:184-, 2012 Cited by PubMed: 22266821DOI: 10.1038/NSMB.2231 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.999 Å) |
Structure validation
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