1U59
Crystal Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine
Summary for 1U59
Entry DOI | 10.2210/pdb1u59/pdb |
Descriptor | Tyrosine-protein kinase ZAP-70, STAUROSPORINE (3 entities in total) |
Functional Keywords | transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P43403 |
Total number of polymer chains | 1 |
Total formula weight | 33714.13 |
Authors | Jin, L.,Pluskey, S.,Petrella, E.C.,Cantin, S.M.,Gorga, J.C.,Rynkiewicz, M.J.,Pandey, P.,Strickler, J.E.,Babine, R.E.,Weaver, D.T.,Seidl, K.J. (deposition date: 2004-07-27, release date: 2004-08-17, Last modification date: 2023-08-23) |
Primary citation | Jin, L.,Pluskey, S.,Petrella, E.C.,Cantin, S.M.,Gorga, J.C.,Rynkiewicz, M.J.,Pandey, P.,Strickler, J.E.,Babine, R.E.,Weaver, D.T.,Seidl, K.J. The Three-dimensional Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine: IMPLICATIONS FOR THE DESIGN OF SELECTIVE INHIBITORS J.Biol.Chem., 279:42818-42825, 2004 Cited by PubMed: 15292186DOI: 10.1074/jbc.M407096200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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