1U59

Crystal Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tyrosine-protein kinase ZAP-70	polymer	287	33247.6	1	UniProt (P43403) Pfam (PF07714) In PDB	Homo sapiens (human)	70 kDa zeta-associated protein, Syk-related tyrosine kinase
2	A	STAUROSPORINE	non-polymer		466.5	1	Chemie (STU)
3		water	water		18.0	54	Chemie (HOH)

Sequence modifications

A: 327 - 606 (UniProt: P43403)

PDB	External Database	Details
His 607	-	expression tag
His 608	-	expression tag
His 609	-	expression tag
His 610	-	expression tag
His 611	-	expression tag
His 612	-	expression tag
His 613	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33247.6
Non-Polymers*	Number of molecules	1
	Total formula weight	466.5
All*	Total formula weight	33714.1

*Water molecules are not included.