2XI4

Torpedo californica Acetylcholinesterase in Complex with Aflatoxin B1 (Orthorhombic Space Group)

2XI4 の概要

• エントリーDOI: 10.2210/pdb2xi4/pdb
• 関連するPDBエントリー: 1ACJ 1ACL 1AMN 1AX9 1CFJ 1DX6 1E3Q 1E66 1EA5 1EEA 1EVE 1FSS 1GPK 1GPN 1GQR 1GQS 1H22 1H23 1HBJ 1JGA 1JGB 1JJB 1OCE 1ODC 1QID 1QIE 1QIF 1QIG 1QIH 1QII 1QIJ 1QIK 1QIM 1QTI 1SOM 1U65 1UT6 1VOT 1VXO 1VXR 1W4L 1W6R 1W75 1W76 1ZGB 1ZGC 2ACE 2ACK 2C4H 2C58 2C5F 2C5G 2CEK 2CKM 2CMF 2DFP 2J3D 2J3Q 2J4F 2V96 2V97 2V98 2VA9 2VB4 2VJA 2VJB 2VJC 2VJD 2VQ6 2VT6 2VT7 2W6C 2W9I 2WFZ 2WG0 2WG1 2WG2 3ACE 4ACE
• 分子名称: ACETYLCHOLINESTERASE, AFLATOXIN B1, CHLORIDE ION, ... (8 entities in total)
• 機能のキーワード: acetylcholinesterase backdoor, mycotoxin, alzheimer disease, cell junction, gpi-anchor, hydrolase, neurotransmitter cleavage, neurotransmitter degradation, serine esterase, synapse
• 由来する生物種: TORPEDO CALIFORNICA (PACIFIC ELECTRIC RAY)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 124321.60

構造登録者

Sanson, B.,Colletier, J.P.,Xu, Y.,Lang, P.T.,Jiang, H.,Silman, I.,Sussman, J.L.,Weik, M. (登録日: 2010-06-28, 公開日: 2011-03-23, 最終更新日: 2023-12-20)

• 主引用文献: Sanson, B.,Colletier, J.P.,Xu, Y.,Lang, P.T.,Jiang, H.,Silman, I.,Sussman, J.L.,Weik, M.; Backdoor Opening Mechanism in Acetylcholinesterase Based on X-Ray Crystallography and Molecular Dynamics Simulations.; Protein Sci., 20:1114-, 2011; PubMed: 21594947; DOI: 10.1002/PRO.661

実験手法

X-RAY DIFFRACTION (2.3 Å)