Summary for 1OI9
| Related | 1AQ1 1B38 1B39 1BUH 1CKP 1DI8 1DM2 1E1V 1E1X 1E9H 1F5Q 1FIN 1FQ1 1FVT 1G5S 1GIH 1GII 1GIJ 1GY3 1GZ8 1H00 1H01 1H06 1H07 1H08 1H0U 1H0V 1H0W 1H24 1H25 1H26 1H27 1H28 1HCK 1HCL 1JSV 1JVP 1KE5 1KE6 1KE7 1KE8 1KE9 1QMZ 1FVV 1H1P 1H1Q 1H1R 1H1S 1JST 1JSU 1OGU |
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| Descriptor | CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, 6-CYCLOHEXYLMETHYLOXY-2-(4'-HYDROXYANILINO)PURINE, ... (6 entities in total) |
| Functional Keywords | kinase, transferase, serine/threonine-protein kinase, atp-binding, cell cycle, cell division, mitosis, phosphorylation |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Nucleus 1OI9 |
| Total number of polymer chains | 4 |
| Total molecular weight | 129398.16 |
| Authors | Pratt, D.J.,Endicott, J.A.,Noble, M.E.M. (deposition date: 2003-06-10, release date: 2004-07-13, Last modification date: 2011-07-13) |
| Primary citation | Hardcastle, I.R.,Arris, C.E.,Bentley, J.,Boyle, F.T.,Chen, Y.,Curtin, N.J.,Endicott, J.A.,Gibson, A.E.,Golding, B.T.,Griffin, R.J.,Jewsbury, P.,Menyerol, J.,Mesguiche, V.,Newell, D.R.,Noble, M.E.M.,Pratt, D.J.,Wang, L.-Z.,Whitfield, H.J. N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2 J.Med.Chem., 47:3710-, 2004 PubMed: 15239650 (PDB entries with the same primary citation) DOI: 10.1021/JM0311442  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
