1JSU

P27(KIP1)/CYCLIN A/CDK2 COMPLEX

Summary for 1JSU

DescriptorCYCLIN-DEPENDENT KINASE-2, CYCLIN A, P27, ... (5 entities in total)
Functional Keywordscomplex (transferase-cyclin-inhibitor), kinase, cell cycle, cell division, cdk, cyclin, inhibitor, complex (transferase-cyclin-inhibitor) complex, complex (transferase/cyclin/inhibitor)
Biological sourceHomo sapiens (human)
Cellular locationNucleus P20248 P46527
Total number of polymer chains3
Total molecular weight73990.2
Authors
Russo, A.A.,Jeffrey, P.D.,Pavletich, N.P. (deposition date: 1996-07-03, release date: 1997-07-29, Last modification date: 2011-07-13)
Primary citation
Russo, A.A.,Jeffrey, P.D.,Patten, A.K.,Massague, J.,Pavletich, N.P.
Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex.
Nature, 382:325-331, 1996
PubMed: 8684460 (PDB entries with the same primary citation)
DOI: 10.1038/382325a0
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers110.8%5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report