1E9H
Thr 160 phosphorylated CDK2 - Human cyclin A3 complex with the inhibitor indirubin-5-sulphonate bound
Summary for 1E9H
Entry DOI | 10.2210/pdb1e9h/pdb |
Related | 1AQ1 1B38 1B39 1CKP 1DM2 1E1V 1E1X 1FIN 1HCK 1HCL 1JST 1JSU 1QMZ |
Descriptor | CELL DIVISION PROTEIN KINASE 2, CYCLIN A3, 2',3-DIOXO-1,1',2',3-TETRAHYDRO-2,3'-BIINDOLE-5'-SULFONIC ACID, ... (4 entities in total) |
Functional Keywords | cell cycle, complex (protein kinase-cyclin), kinases, inhibitor, cyclin, complex, phosphorylation |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus: P20248 |
Total number of polymer chains | 4 |
Total formula weight | 128360.47 |
Authors | Davies, T.G.,Tunnah, P.,Noble, M.E.M.,Endicott, J.A. (deposition date: 2000-10-16, release date: 2001-10-11, Last modification date: 2024-05-01) |
Primary citation | Davies, T.G.,Tunnah, P.,Meijer, L.,Marko, D.,Eisenbrand, G.,Endicott, J.A.,Noble, M.E. Inhibitor Binding to Active and Inactive Cdk2: The Crystal Structure of Cdk2-Cyclin A/Indirubin-5-Sulphonate Structure, 9:389-, 2001 Cited by PubMed: 11377199DOI: 10.1016/S0969-2126(01)00598-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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