1HCL

HUMAN CYCLIN-DEPENDENT KINASE 2

Summary for 1HCL

Related1HCK
DescriptorHUMAN CYCLIN-DEPENDENT KINASE 2 (2 entities in total)
Functional Keywordstransferase, serine/threonine protein kinase, atp-binding, cell cycle, cell division, mitosis, phosphorylation, protein kinase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total molecular weight33976.49
Authors
Schulze-Gahmen, U.,De Bondt, H.L.,Kim, S.-H. (deposition date: 1996-06-03, release date: 1996-12-07, Last modification date: 2011-07-13)
Primary citation
Schulze-Gahmen, U.,De Bondt, H.L.,Kim, S.H.
High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design.
J.Med.Chem., 39:4540-4546, 1996
PubMed: 8917641 (PDB entries with the same primary citation)
DOI: 10.1021/jm960402a
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers140.3%9.3%3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution