1GY3

pCDK2/cyclin A in complex with MgADP, nitrate and peptide substrate

Summary for 1GY3

Related1AQ1 1B38 1B39 1BUH 1CKP 1DI8 1DM2 1E1V 1E1X 1E9H 1F5Q 1FIN 1FQ1 1FVT 1FVV 1G5S 1GIH 1GII 1GIJ 1HCK 1HCL 1JST 1JSU 1JSV 1JVP 1QMZ
DescriptorCELL DIVISION PROTEIN KINASE 2, CYCLIN A2, SUBSTRATE PEPTIDE, ... (8 entities in total)
Functional Keywordstransferase-transferase substrate complex, cell cycle regulatory protein kinase, thr160-phospho-cyclin dependent protein kinase 2 in association with cyclin a, transferase- transferase substrate complex, transferase/transferase substrate
Biological sourceHOMO SAPIENS (HUMAN)
More
Total number of polymer chains6
Total molecular weight130578.76
Authors
Cook, A.,Lowe, E.D.,Chrysina, E.D.,Skamnaki, V.T.,Oikonomakos, N.G.,Johnson, L.N. (deposition date: 2002-04-19, release date: 2002-04-29, Last modification date: 2019-05-15)
Primary citation
Cook, A.,Lowe, E.D.,Chrysina, E.D.,Skamnaki, V.T.,Oikonomakos, N.G.,Johnson, L.N.
Structural Studies on Phospho-Cdk2/Cyclin a Bound to Nitrate, a Transition State Analogue: Implications for the Protein Kinase Mechanism
Biochemistry, 41:7301-, 2002
PubMed: 12044161 (PDB entries with the same primary citation)
DOI: 10.1021/BI0201724
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.31533 1.4% 8.2% 3.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report