5XA5
 
 | | Crystal structure of HMP-1-HMP-2 complex | | Descriptor: | Alpha-catenin-like protein hmp-1, Beta-catenin-like protein hmp-2 | | Authors: | Shao, X, Kang, H, Weis, W.I, Hardin, J, Choi, H.J. | | Deposit date: | 2017-03-11 | | Release date: | 2017-08-30 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Cell-cell adhesion in metazoans relies on evolutionarily conserved features of the alpha-catenin· beta-catenin-binding interface.
J.Biol.Chem., 292, 2017
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3RF3
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1ZVZ
 | | Vinculin Head (0-258) in Complex with the Talin Rod Residue 820-844 | | Descriptor: | Talin 1, Vinculin | | Authors: | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | | Deposit date: | 2005-06-03 | | Release date: | 2005-09-20 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
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1QKR
 | | Crystal structure of the vinculin tail and a pathway for activation | | Descriptor: | SULFATE ION, VINCULIN | | Authors: | Bakolitsa, C, De Pereda, J.M, Bagshaw, C.R, Critchley, D.R, Liddington, R.C. | | Deposit date: | 1999-08-04 | | Release date: | 2000-08-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of the Vinculin Tail and a Pathway for Activation
Cell(Cambridge,Mass.), 99, 1999
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1YDI
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3S90
 | | Human vinculin head domain Vh1 (residues 1-252) in complex with murine talin (VBS33; residues 1512-1546) | | Descriptor: | Talin-1, Vinculin | | Authors: | Yogesha, S.D, Sharff, A, Bricogne, G, Izard, T. | | Deposit date: | 2011-05-31 | | Release date: | 2011-06-22 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Intermolecular versus intramolecular interactions of the vinculin binding site 33 of talin.
Protein Sci., 20, 2011
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3TJ5
 | | human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-N; residues 412-434) from Rickettsia rickettsii | | Descriptor: | Antigenic heat-stable 120 kDa protein, GLYCEROL, Vinculin | | Authors: | Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T. | | Deposit date: | 2011-08-23 | | Release date: | 2011-09-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
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1T01
 | | Vinculin complexed with the VBS1 helix from talin | | Descriptor: | Talin 1, unnamed protein product | | Authors: | Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J. | | Deposit date: | 2004-04-07 | | Release date: | 2004-08-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
Embo J., 23, 2004
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1ZW2
 | | Vinculin Head (0-258) in Complex with the Talin Rod residues 2345-2369 | | Descriptor: | Vinculin, talin | | Authors: | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | | Deposit date: | 2005-06-03 | | Release date: | 2005-09-20 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
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1H6G
 | | alpha-catenin M-domain | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ALPHA-1 CATENIN, CALCIUM ION, ... | | Authors: | Yang, J, Dokurno, P, Tonks, N.K, Barford, D. | | Deposit date: | 2001-06-14 | | Release date: | 2001-08-07 | | Last modified: | 2016-02-10 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of the M-Fragment of Alpha-Catenin: Implications for Modulation of Cell Adhesion.
Embo J., 20, 2001
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6DUW
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3MYI
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4DJ9
 | | Human vinculin head domain Vh1 (residues 1-258) in complex with the talin vinculin binding site 50 (VBS50, residues 2078-2099) | | Descriptor: | Talin-1, Vinculin | | Authors: | Yogesha, S.D, Rangarajan, E.S, Vonrhein, C, Bricogne, G, Izard, T. | | Deposit date: | 2012-02-01 | | Release date: | 2012-02-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin.
Protein Sci., 21, 2012
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3ZDL
 | | Vinculin head (1-258) in complex with a RIAM fragment | | Descriptor: | AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN, VINCULIN | | Authors: | Zacharchenko, T, Elliott, P.R, Goult, B.T, Bate, N, Critchely, D.R, Barsukov, I.L. | | Deposit date: | 2012-11-28 | | Release date: | 2013-02-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Riam and Vinculin Binding to Talin are Mutually Exclusive and Regulate Adhesion Assembly and Turnover.
J.Biol.Chem., 288, 2013
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6BFI
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4E17
 | | Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin | | Descriptor: | Catenin alpha-1, Vinculin | | Authors: | Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I. | | Deposit date: | 2012-03-05 | | Release date: | 2012-05-16 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.304 Å) | | Cite: | Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
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1RKE
 | | Human vinculin head (1-258) in complex with human vinculin tail (879-1066) | | Descriptor: | VCL protein, Vinculin | | Authors: | Izard, T, Evans, G, Borgon, R.A, Rush, C.L, Bricogne, G, Bois, P.R. | | Deposit date: | 2003-11-21 | | Release date: | 2004-01-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Vinculin activation by talin through helical bundle conversion
Nature, 427, 2004
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1U6H
 | | Vinculin head (0-258) in complex with the talin vinculin binding site 2 (849-879) | | Descriptor: | Talin, Vinculin | | Authors: | Fillingham, I, Gingras, A.R, Papagrigoriou, E, Patel, B, Emsley, J, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. | | Deposit date: | 2004-07-30 | | Release date: | 2005-01-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.
Structure, 13, 2005
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5H5M
 | | Crystal structure of HMP-1 M domain | | Descriptor: | Alpha-catenin-like protein hmp-1 | | Authors: | Kang, H, Bang, I, Weis, W.I, Choi, H.J. | | Deposit date: | 2016-11-08 | | Release date: | 2017-03-29 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and functional characterization of Caenorhabditis elegans alpha-catenin reveals constitutive binding to beta-catenin and F-actin
J. Biol. Chem., 292, 2017
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4E18
 | | Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin | | Descriptor: | Catenin alpha-1, Vinculin | | Authors: | Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I. | | Deposit date: | 2012-03-05 | | Release date: | 2012-05-16 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.403 Å) | | Cite: | Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
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1SYQ
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5XFL
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5L0I
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1L7C
 | | alpha-catenin fragment, residues 385-651 | | Descriptor: | Alpha E-catenin | | Authors: | Pokutta, S, Drees, F, Takai, Y, Nelson, W.J, Weis, W.I. | | Deposit date: | 2002-03-14 | | Release date: | 2002-06-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Biochemical and structural definition of the l-afadin- and actin-binding sites of alpha-catenin.
J.Biol.Chem., 277, 2002
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4P9T
 | | Structure of the free form of the N-terminal VH1 domain of monomeric alpha-catenin | | Descriptor: | 1,2-ETHANEDIOL, Catenin alpha-2, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Shibahara, T, Hirano, Y, Hakoshima, T. | | Deposit date: | 2014-04-04 | | Release date: | 2015-04-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the free form of the N-terminal VH1 domain of monomeric alpha-catenin.
Febs Lett., 589, 2015
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