1PGJ
  • Download 1pgj
  • View 1pgj
Molmil generated image of 1pgj
X-RAY STRUCTURE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE FROM THE PROTOZOAN PARASITE T. BRUCEI
Descriptor:6-PHOSPHOGLUCONATE DEHYDROGENASE, SULFATE ION
Authors:Dohnalek, J., Phillips, C., Gover, S., Barrett, M.P., Adams, M.J.
Deposit date:1998-03-16
Release date:1998-11-11
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:A 2.8 A resolution structure of 6-phosphogluconate dehydrogenase from the protozoan parasite Trypanosoma brucei: comparison with the sheep enzyme accounts for differences in activity with coenzyme and substrate analogues.
J.Mol.Biol., 282, 1998
1PGN
  • Download 1pgn
  • View 1pgn
Molmil generated image of 1pgn
CRYSTALLOGRAPHIC STUDY OF COENZYME, COENZYME ANALOGUE AND SUBSTRATE BINDING IN 6-PHOSPHOGLUCONATE DEHYDROGENASE: IMPLICATIONS FOR NADP SPECIFICITY AND THE ENZYME MECHANISM
Descriptor:6-PHOSPHOGLUCONATE DEHYDROGENASE, SULFATE ION, NICOTINAMIDE 8-BROMO-ADENINE DINUCLEOTIDE PHOSPHATE, ...
Authors:Adams, M.J., Phillips, C., Gover, S.
Deposit date:1994-07-18
Release date:1995-02-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism.
Structure, 2, 1994
1PGO
  • Download 1pgo
  • View 1pgo
Molmil generated image of 1pgo
CRYSTALLOGRAPHIC STUDY OF COENZYME, COENZYME ANALOGUE AND SUBSTRATE BINDING IN 6-PHOSPHOGLUCONATE DEHYDROGENASE: IMPLICATIONS FOR NADP SPECIFICITY AND THE ENZYME MECHANISM
Descriptor:6-PHOSPHOGLUCONATE DEHYDROGENASE, SULFATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Adams, M.J., Phillips, C., Gover, S.
Deposit date:1994-07-18
Release date:1995-02-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism.
Structure, 2, 1994
1PGP
  • Download 1pgp
  • View 1pgp
Molmil generated image of 1pgp
CRYSTALLOGRAPHIC STUDY OF COENZYME, COENZYME ANALOGUE AND SUBSTRATE BINDING IN 6-PHOSPHOGLUCONATE DEHYDROGENASE: IMPLICATIONS FOR NADP SPECIFICITY AND THE ENZYME MECHANISM
Descriptor:6-PHOSPHOGLUCONATE DEHYDROGENASE, 6-PHOSPHOGLUCONIC ACID, SULFATE ION
Authors:Adams, M.J., Phillips, C., Gover, S., Naylor, C.E.
Deposit date:1994-07-18
Release date:1995-02-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism.
Structure, 2, 1994
1PGQ
  • Download 1pgq
  • View 1pgq
Molmil generated image of 1pgq
CRYSTALLOGRAPHIC STUDY OF COENZYME, COENZYME ANALOGUE AND SUBSTRATE BINDING IN 6-PHOSPHOGLUCONATE DEHYDROGENASE: IMPLICATIONS FOR NADP SPECIFICITY AND THE ENZYME MECHANISM
Descriptor:6-PHOSPHOGLUCONATE DEHYDROGENASE, SULFATE ION, ADENOSINE-2'-MONOPHOSPHATE
Authors:Adams, M.J., Phillips, C., Gover, S.
Deposit date:1994-07-18
Release date:1995-02-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism.
Structure, 2, 1994
2IYO
  • Download 2iyo
  • View 2iyo
Molmil generated image of 2iyo
STRUCTURAL CHARACTERIZATION OF A BACTERIAL 6PDH REVEALS ASPECTS OF SPECIFICITY, MECHANISM AND MODE OF INHIBITION
Descriptor:6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, 6-PHOSPHOGLUCONIC ACID, ...
Authors:Sundaramoorthy, R., Iulek, J., Hunter, W.N.
Deposit date:2006-07-21
Release date:2007-01-23
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of a Bacterial 6-Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates.
FEBS J., 274, 2007
2IYP
  • Download 2iyp
  • View 2iyp
Molmil generated image of 2iyp
PRODUCT RUP
Descriptor:6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Sundaramoorthy, R., Iulek, J., Hunter, W.N.
Deposit date:2006-07-21
Release date:2007-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Crystal Structures of a Bacterial 6-Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates.
FEBS J., 274, 2007
2IZ0
  • Download 2iz0
  • View 2iz0
Molmil generated image of 2iz0
PEX INHIBITOR-HOME DATA
Descriptor:6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Sundaramoorthy, R., Iulek, J., Hunter, W.N.
Deposit date:2006-07-23
Release date:2007-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of a Bacterial 6- Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates.
FEBS J., 274, 2007
2IZ1
  • Download 2iz1
  • View 2iz1
Molmil generated image of 2iz1
6PDH COMPLEXED WITH PEX INHIBITOR SYNCHROTRON DATA
Descriptor:6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, ...
Authors:Sundaramoorthy, R., Iulek, J., Hunter, W.N.
Deposit date:2006-07-23
Release date:2007-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of a Bacterial 6- Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates.
FEBS J., 274, 2007
2JKV
  • Download 2jkv
  • View 2jkv
Molmil generated image of 2jkv
STRUCTURE OF HUMAN PHOSPHOGLUCONATE DEHYDROGENASE IN COMPLEX WITH NADPH AT 2.53A
Descriptor:6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Pilka, E.S., Kavanagh, K.L., von Delft, F., Muniz, J.R.C., Murray, J., Picaud, S., Guo, K., Edwards, A., Arrowsmith, C.H., Weigelt, J., Bountra, C., Oppermann, U.
Deposit date:2008-09-01
Release date:2009-09-01
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (2.532 Å)
Cite:Structure of Human Phosphogluconate Dehydrogenase in Complex with Nadph at 2.53A
To be Published
2P4Q
  • Download 2p4q
  • View 2p4q
Molmil generated image of 2p4q
CRYSTAL STRUCTURE ANALYSIS OF GND1 IN SACCHAROMYCES CEREVISIAE
Descriptor:6-phosphogluconate dehydrogenase, decarboxylating 1, CITRATE ANION
Authors:He, W., Wang, Y., Liu, W., Zhou, C.Z.
Deposit date:2007-03-12
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1
Bmc Struct.Biol., 7, 2007
2PGD
  • Download 2pgd
  • View 2pgd
Molmil generated image of 2pgd
THE STRUCTURE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE REFINED AT 2 ANGSTROMS RESOLUTION
Descriptor:6-PHOSPHOGLUCONATE DEHYDROGENASE, SULFATE ION
Authors:Adams, M.J., Phillips, C., Gover, S.
Deposit date:1994-07-18
Release date:1995-02-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of 6-phosphogluconate dehydrogenase refined at 2.5 A resolution.
Acta Crystallogr.,Sect.B, 47, 1991
2W8Z
  • Download 2w8z
  • View 2w8z
Molmil generated image of 2w8z
GEOBACILLUS STEAROTHERMOPHILUS 6-PHOSPHOGLUCONATE DEHYDROGENASE WITH BOUND 6- PHOSPHOGLUCONATE
Descriptor:6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, 6-PHOSPHOGLUCONIC ACID, ...
Authors:Cameron, S., Hunter, W.N.
Deposit date:2009-01-20
Release date:2009-04-07
Last modified:2012-05-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Geobacillus Stearothermophilus 6-Phosphogluconate Dehydrogenase, Complexed with 6-Phosphogluconate.
Acta Crystallogr.,Sect.F, 65, 2009
2ZYA
  • Download 2zya
  • View 2zya
Molmil generated image of 2zya
DIMERIC 6-PHOSPHOGLUCONATE DEHYDROGENASE COMPLEXED WITH 6-PHOSPHOGLUCONATE
Descriptor:6-phosphogluconate dehydrogenase, decarboxylating, 6-PHOSPHOGLUCONIC ACID
Authors:Chen, Y.-Y., Ko, T.-P., Lo, L.-P., Lin, C.-H., Wang, A.H.-J.
Deposit date:2009-01-19
Release date:2009-09-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
2ZYD
  • Download 2zyd
  • View 2zyd
Molmil generated image of 2zyd
DIMERIC 6-PHOSPHOGLUCONATE DEHYDROGENASE COMPLEXED WITH GLUCOSE
Descriptor:6-phosphogluconate dehydrogenase, decarboxylating, D-GLUCOSE IN LINEAR FORM
Authors:Chen, Y.-Y., Ko, T.-P., Lo, L.-P., Lin, C.-H., Wang, A.H.-J.
Deposit date:2009-01-19
Release date:2009-09-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
2ZYG
  • Download 2zyg
  • View 2zyg
Molmil generated image of 2zyg
APO-FORM OF DIMERIC 6-PHOSPHOGLUCONATE DEHYDROGENASE
Descriptor:6-phosphogluconate dehydrogenase, decarboxylating
Authors:Chen, Y.-Y., Ko, T.-P., Lo, L.-P., Lin, C.-H., Wang, A.H.-J.
Deposit date:2009-01-21
Release date:2009-09-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
3FWN
  • Download 3fwn
  • View 3fwn
Molmil generated image of 3fwn
DIMERIC 6-PHOSPHOGLUCONATE DEHYDROGENASE COMPLEXED WITH 6-PHOSPHOGLUCONATE AND 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE
Descriptor:6-phosphogluconate dehydrogenase, decarboxylating, 6-PHOSPHOGLUCONIC ACID, ...
Authors:Chen, Y.-Y., Ko, T.-P., Lo, L.-P., Lin, C.-H., Wang, A.H.-J.
Deposit date:2009-01-19
Release date:2009-09-01
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
4E21
  • Download 4e21
  • View 4e21
Molmil generated image of 4e21
THE CRYSTAL STRUCTURE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE FROM GEOBACTER METALLIREDUCENS
Descriptor:6-phosphogluconate dehydrogenase (Decarboxylating), (4R)-2-METHYLPENTANE-2,4-DIOL
Authors:Zhang, Z., Chamala, S., Evans, B., Foti, R., Gizzi, A., Hillerich, B., Kar, A., Lafleur, J., Seidel, R., Villigas, G., Zencheck, W., Almo, S.C., Swaminathan, S., New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2012-03-07
Release date:2012-03-21
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:The crystal structure of 6-phosphogluconate dehydrogenase from Geobacter metallireducens
To be Published
4GWG
  • Download 4gwg
  • View 4gwg
Molmil generated image of 4gwg
CRYSTAL STRUCTURE ANALYSIS OF 6-PHOSPHOGLUCONATE DEHYDROGENASE APO-FORM
Descriptor:6-phosphogluconate dehydrogenase, decarboxylating, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:He, C., Zhou, L., Zhang, L.
Deposit date:2012-09-03
Release date:2012-11-28
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.3907 Å)
Cite:Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.
Cancer Cell, 22, 2012
4GWK
  • Download 4gwk
  • View 4gwk
Molmil generated image of 4gwk
CRYSTAL STRUCTURE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE COMPLEXED WITH 3-PHOSPHOGLYCERIC ACID
Descriptor:6-phosphogluconate dehydrogenase, decarboxylating, 3-PHOSPHOGLYCERIC ACID, ...
Authors:He, C., Zhou, L., Zhang, L.
Deposit date:2012-09-03
Release date:2012-11-28
Method:X-RAY DIFFRACTION (1.534 Å)
Cite:Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.
Cancer Cell, 22, 2012
5UQ9
  • Download 5uq9
  • View 5uq9
Molmil generated image of 5uq9
CRYSTAL STRUCTURE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE WITH ((4R,5R)-5-(HYDROXYCARBAMOYL)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YL)METHYL DIHYDROGEN PHOSPHATE
Descriptor:6-phosphogluconate dehydrogenase, decarboxylating, [(4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl dihydrogen phosphate
Authors:Leonard, P.G.
Deposit date:2017-02-07
Release date:2018-08-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Functional genomics reveals dependency on phosphogluconate dehydrogenease in OXPHOS-deficient tumors
To Be Published
6FQX
  • Download 6fqx
  • View 6fqx
Molmil generated image of 6fqx
PLASMODIUM FALCIPARUM 6-PHOSPHOGLUCONATE DEHYDROGENASE IN ITS APO FORM, IN COMPLEX WITH ITS COFACTOR NADP+ AND IN COMPLEX WITH ITS SUBSTRATE 6-PHOSPHOGLUCONATE
Descriptor:6-phosphogluconate dehydrogenase, decarboxylating, GLYCEROL, ...
Authors:Fritz-Wolf, K., Haeussler, K., Reichmann, M., Rahlfs, S., Becker, K.
Deposit date:2018-02-15
Release date:2018-08-22
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target.
J. Mol. Biol., 430, 2018
6FQY
  • Download 6fqy
  • View 6fqy
Molmil generated image of 6fqy
PLASMODIUM FALCIPARUM 6-PHOSPHOGLUCONATE DEHYDROGENASE IN ITS APO FORM, IN COMPLEX WITH ITS COFACTOR NADP+ AND IN COMPLEX WITH ITS SUBSTRATE 6-PHOSPHOGLUCONATE
Descriptor:6-phosphogluconate dehydrogenase, decarboxylating, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Fritz-Wolf, K., Haeussler, K., Reichmann, M., Rahlfs, S., Becker, K.
Deposit date:2018-02-15
Release date:2018-08-22
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target.
J. Mol. Biol., 430, 2018
6FQZ
  • Download 6fqz
  • View 6fqz
Molmil generated image of 6fqz
PLASMODIUM FALCIPARUM 6-PHOSPHOGLUCONATE DEHYDROGENASE IN ITS APO FORM, IN COMPLEX WITH ITS COFACTOR NADP+ AND IN COMPLEX WITH ITS SUBSTRATE 6-PHOSPHOGLUCONATE
Descriptor:6-phosphogluconate dehydrogenase, decarboxylating, 6-PHOSPHOGLUCONIC ACID, ...
Authors:Fritz-Wolf, K., Haeussler, K., Reichmann, M., Rahlfs, S., Becker, K.
Deposit date:2018-02-15
Release date:2018-08-22
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target.
J. Mol. Biol., 430, 2018
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2018 Protein Data Bank Japan