6FQY

Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate

Summary for 6FQY

Entry DOI	10.2210/pdb6fqy/pdb
Related	6FQY 6FQZ 6fqx
Descriptor	6-phosphogluconate dehydrogenase, decarboxylating, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	plasmodium, complex, substrate, redoxregulation, oxidoreductase
Biological source	Plasmodium falciparum 3D7
Total number of polymer chains	2
Total formula weight	107722.70
Authors	Fritz-Wolf, K.,Haeussler, K.,Reichmann, M.,Rahlfs, S.,Becker, K. (deposition date: 2018-02-15, release date: 2018-08-22, Last modification date: 2024-01-17)
Primary citation	Haeussler, K.,Fritz-Wolf, K.,Reichmann, M.,Rahlfs, S.,Becker, K. Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target. J. Mol. Biol., 430:4049-4067, 2018 Cited by PubMed: 30098336 DOI: 10.1016/j.jmb.2018.07.030 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation