2J4Y
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CRYSTAL STRUCTURE OF A RHODOPSIN STABILIZING MUTANT EXPRESSED IN MAMMALIAN CELLS
Descriptor:RHODOPSIN, RETINAL, N-ACETYL-D-GLUCOSAMINE
Authors:Standfuss, J., Xie, G., Edwards, P.C., Burghammer, M., Oprian, D.D., Schertler, G.F.X.
Deposit date:2006-09-07
Release date:2007-09-25
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of a Thermally Stable Rhodopsin Mutant.
J.Mol.Biol., 372, 2007
2PED
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CRYSTALLOGRAPHIC MODEL OF 9-CIS-RHODOPSIN
Descriptor:Rhodopsin, ALPHA-D-MANNOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Nakamichi, H., Okada, T.
Deposit date:2007-04-02
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Photoisomerization mechanism of rhodopsin and 9-cis-rhodopsin revealed by x-ray crystallography
Biophys.J., 92, 2007
2X72
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CRYSTAL STRUCTURE OF THE CONSTITUTIVELY ACTIVE E113Q,D2C,D282C RHODOPSIN MUTANT WITH BOUND GALPHACT PEPTIDE.
Descriptor:RHODOPSIN, GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
Authors:Standfuss, J., Edwards, P.C., Dantona, A., Fransen, M., Xie, G., Oprian, D.D., Schertler, G.F.X.
Deposit date:2010-02-22
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Structural Basis of Agonist Induced Activation in Constitutively Active Rhodopsin
Nature, 471, 2011
2Z73
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CRYSTAL STRUCTURE OF SQUID RHODOPSIN
Descriptor:Rhodopsin, B-OCTYLGLUCOSIDE, RETINAL, ...
Authors:Murakami, M., Kouyama, T.
Deposit date:2007-08-13
Release date:2008-05-13
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of squid rhodopsin.
Nature, 453, 2008
3AYM
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CRYSTAL STRUCTURE OF THE BATHO INTERMEDIATE OF SQUID RHODOPSIN
Descriptor:Rhodopsin, PALMITIC ACID, B-OCTYLGLUCOSIDE, ...
Authors:Murakami, M., Kouyama, T.
Deposit date:2011-05-09
Release date:2011-08-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic Analysis of the Primary Photochemical Reaction of Squid Rhodopsin
J.Mol.Biol., 413, 2011
3AYN
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CRYSTAL STRUCTURE OF SQUID ISORHODOPSIN
Descriptor:Rhodopsin, RETINAL, PALMITIC ACID, ...
Authors:Murakami, M., Kouyama, T.
Deposit date:2011-05-09
Release date:2011-08-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystallographic Analysis of the Primary Photochemical Reaction of Squid Rhodopsin
J.Mol.Biol., 413, 2011
3C9L
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STRUCTURE OF GROUND-STATE BOVINE RHODOSPIN IN A HEXAGONAL CRYSTAL FORM
Descriptor:Rhodopsin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Stenkamp, R.E.
Deposit date:2008-02-16
Release date:2008-08-05
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.646 Å)
Cite:Alternative models for two crystal structures of bovine rhodopsin.
Acta Crystallogr.,Sect.D, 64, 2008
3C9M
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STRUCTURE OF A MUTANT BOVINE RHODOPSIN IN HEXAGONAL CRYSTAL FORM
Descriptor:Rhodopsin, N-ACETYL-D-GLUCOSAMINE, ACETYL GROUP, ...
Authors:Stenkamp, R.E.
Deposit date:2008-02-16
Release date:2008-08-05
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Alternative models for two crystal structures of bovine rhodopsin.
Acta Crystallogr.,Sect.D, 64, 2008
3CAP
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CRYSTAL STRUCTURE OF NATIVE OPSIN: THE G PROTEIN-COUPLED RECEPTOR RHODOPSIN IN ITS LIGAND-FREE STATE
Descriptor:Rhodopsin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Park, J.H., Scheerer, P., Hofmann, K.P., Choe, H.-W., Ernst, O.P.
Deposit date:2008-02-20
Release date:2008-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the ligand-free G-protein-coupled receptor opsin
Nature, 454, 2008
3DQB
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CRYSTAL STRUCTURE OF THE ACTIVE G-PROTEIN-COUPLED RECEPTOR OPSIN IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM THE GALPHA SUBUNIT OF TRANSDUCIN
Descriptor:Rhodopsin, 11meric peptide form Guanine nucleotide-binding protein G(t) subunit alpha-1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Scheerer, P., Park, J.H., Hildebrand, P.W., Kim, Y.J., Krauss, N., Choe, H.-W., Hofmann, K.P., Ernst, O.P.
Deposit date:2008-07-09
Release date:2008-09-23
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of opsin in its G-protein-interacting conformation
Nature, 455, 2008
3OAX
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CRYSTAL STRUCTURE OF BOVINE RHODOPSIN WITH BETA-IONONE
Descriptor:Rhodopsin, BETA-D-MANNOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Makino, C.L., Riley, C.K., Looney, J., Crouch, R.K., Okada, T.
Deposit date:2010-08-05
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Binding of more than one retinoid to visual opsins
Biophys.J., 99, 2010
3PQR
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CRYSTAL STRUCTURE OF METARHODOPSIN II IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM THE GALPHA SUBUNIT OF TRANSDUCIN
Descriptor:Rhodopsin, Guanine nucleotide-binding protein G(t) subunit alpha-1, RETINAL, ...
Authors:Choe, H.-W., Kim, Y.J., Park, J.H., Morizumi, T., Pai, E.F., Krauss, N., Hofmann, K.P., Scheerer, P., Ernst, O.P.
Deposit date:2010-11-26
Release date:2011-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of metarhodopsin II.
Nature, 471, 2011
3PXO
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CRYSTAL STRUCTURE OF METARHODOPSIN II
Descriptor:Rhodopsin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Choe, H.-W., Kim, Y.J., Park, J.H., Morizumi, T., Pai, E.F., Krauss, N., Hofmann, K.P., Scheerer, P., Ernst, O.P.
Deposit date:2010-12-10
Release date:2011-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of metarhodopsin II.
Nature, 471, 2011
4A4M
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CRYSTAL STRUCTURE OF THE LIGHT-ACTIVATED CONSTITUTIVELY ACTIVE N2C, M257Y,D282C RHODOPSIN MUTANT IN COMPLEX WITH A PEPTIDE RESEMBLING THE C-TERMINUS OF THE GALPHA-PROTEIN SUBUNIT (GACT)
Descriptor:RHODOPSIN, GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-3, RETINAL, ...
Authors:Deupi, X., Edwards, P., Singhal, A., Nickle, B., Oprian, D.D., Schertler, G.F.X., Standfuss, J.
Deposit date:2011-10-17
Release date:2012-01-25
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Stabilized G Protein Binding Site in the Structure of Constitutively Active Metarhodopsin-II.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BEY
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NIGHT BLINDNESS CAUSING G90D RHODOPSIN IN COMPLEX WITH GACT2 PEPTIDE
Descriptor:Rhodopsin, Guanine nucleotide-binding protein G(t) subunit alpha-1, SULFATE ION, ...
Authors:Singhal, A., Ostermaier, M.K., Vishnivetskiy, S.A., Panneels, V., Homan, K.T., Tesmer, J.J.G., Veprintsev, D., Deupi, X., Gurevich, V.V., Schertler, G.F.X., Standfuss, J.
Deposit date:2013-03-12
Release date:2013-05-08
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Insights Into Congenital Stationary Night Blindness Based on the Structure of G90D Rhodopsin.
Embo Rep., 14, 2013
4BEZ
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NIGHT BLINDNESS CAUSING G90D RHODOPSIN IN THE ACTIVE CONFORMATION
Descriptor:RHODOPSIN, ACETATE ION, SULFATE ION, ...
Authors:Singhal, A., Ostermaier, M.K., Vishnivetskiy, S.A., Panneels, V., Homan, K.T., Tesmer, J.J.G., Veprintsev, D., Deupi, X., Gurevich, V.V., Schertler, G.F.X., Standfuss, J.
Deposit date:2013-03-12
Release date:2013-04-24
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Insights Into Congenital Stationary Night Blindness Based on the Structure of G90D Rhodopsin.
Embo Rep., 14, 2013
4GBR
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N-TERMINAL T4 LYSOZYME FUSION FACILITATES CRYSTALLIZATION OF A G PROTEIN COUPLED RECEPTOR
Descriptor:Beta-2 adrenergic receptor, Lysozyme, (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol
Authors:Zou, Y., Weis, W.I., Kobilka, B.K.
Deposit date:2012-07-27
Release date:2012-10-24
Method:X-RAY DIFFRACTION (3.993 Å)
Cite:N-terminal t4 lysozyme fusion facilitates crystallization of a g protein coupled receptor.
Plos One, 7, 2012
4J4Q
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CRYSTAL STRUCTURE OF ACTIVE CONFORMATION OF GPCR OPSIN STABILIZED BY OCTYLGLUCOSIDE
Descriptor:Rhodopsin, Guanine nucleotide-binding protein G(t) subunit alpha-1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Park, J.H., Morizumi, T., Li, Y., Hong, J.E., Pai, E.F., Hofmann, K.P., Choe, H.W., Ernst, O.P.
Deposit date:2013-02-07
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Opsin, a structural model for olfactory receptors?
Angew.Chem.Int.Ed.Engl., 52, 2013
4PHU
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CRYSTAL STRUCTURE OF HUMAN GPR40 BOUND TO ALLOSTERIC AGONIST TAK-875
Descriptor:Free fatty acid receptor 1,Lysozyme, [(3S)-6-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy]biphenyl-3-yl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
Authors:Srivastava, A., Yano, J.K., Hirozane, Y., Kefala, G., Snell, G., Lane, W., Gruswitz, F., Ivetac, A., Aertgeerts, K., Nguyen, J., Jennings, A., Okada, K.
Deposit date:2014-05-07
Release date:2014-07-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.332 Å)
Cite:High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875.
Nature, 513, 2014
4PXF
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CRYSTAL STRUCTURE OF THE ACTIVE G-PROTEIN-COUPLED RECEPTOR OPSIN IN COMPLEX WITH THE FINGER-LOOP PEPTIDE DERIVED FROM THE FULL-LENGTH ARRESTIN-1
Descriptor:Rhodopsin, S-arrestin, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Szczepek, M., Scheerer, P.
Deposit date:2014-03-23
Release date:2014-09-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of a common GPCR-binding interface for G protein and arrestin.
Nat Commun, 5, 2014
4S0V
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CRYSTAL STRUCTURE OF THE HUMAN OX2 OREXIN RECEPTOR BOUND TO THE INSOMNIA DRUG SUVOREXANT
Descriptor:Human Orexin receptor type 2 fusion protein to P. abysii Glycogen Synthase, [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone, OLEIC ACID
Authors:Yin, J., Kolb, P., Mobarec, J.C., Rosenbaum, D.M.
Deposit date:2015-01-06
Release date:2015-01-14
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant.
Nature, 519, 2015
4X1H
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OPSIN/G(ALPHA) PEPTIDE COMPLEX STABILIZED BY NONYL-GLUCOSIDE
Descriptor:Rhodopsin, C-terminal derived peptide of guanine nucleotide-binding protein G(t) subunit alpha-1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Blankenship, E., Lodowski, D.T.
Deposit date:2014-11-24
Release date:2015-11-04
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:The High-Resolution Structure of Activated Opsin Reveals a Conserved Solvent Network in the Transmembrane Region Essential for Activation.
Structure, 23, 2015
4XT1
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STRUCTURE OF A NANOBODY-BOUND VIRAL GPCR BOUND TO HUMAN CHEMOKINE CX3CL1
Descriptor:G-protein coupled receptor homolog US28, Fractalkine, nanobody 7, ...
Authors:Burg, J.S., Jude, K.M., Waghray, D., Garcia, K.C.
Deposit date:2015-01-22
Release date:2015-03-04
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.886 Å)
Cite:Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.
Science, 347, 2015
4XT3
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STRUCTURE OF A VIRAL GPCR BOUND TO HUMAN CHEMOKINE CX3CL1
Descriptor:G-protein coupled receptor homolog US28, Fractalkine, UNKNOWN LIGAND, ...
Authors:Burg, J.S., Jude, K.M., Waghray, D., Garcia, K.C.
Deposit date:2015-01-22
Release date:2015-03-04
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (3.801 Å)
Cite:Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.
Science, 347, 2015
4ZJ8
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STRUCTURES OF THE HUMAN OX1 OREXIN RECEPTOR BOUND TO SELECTIVE AND DUAL ANTAGONISTS
Descriptor:human OX1R fusion protein to P.abysii glycogen synthase, [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone, OLEIC ACID
Authors:Yin, J., Brautigam, C.A., Shao, Z., Clark, L., Harrell, C.M., Gotter, A.L., Coleman, P., Renger, J.J., Rosenbaum, D.M.
Deposit date:2015-04-29
Release date:2016-03-09
Last modified:2016-04-13
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors.
Nat.Struct.Mol.Biol., 23, 2016