2J4Y | | CRYSTAL STRUCTURE OF A RHODOPSIN STABILIZING MUTANT EXPRESSED IN MAMMALIAN CELLS | | Descriptor: | RHODOPSIN, RETINAL, N-ACETYL-D-GLUCOSAMINE | | Authors: | Standfuss, J., Xie, G., Edwards, P.C., Burghammer, M., Oprian, D.D., Schertler, G.F.X. | | Deposit date: | 2006-09-07 | | Release date: | 2007-09-25 | | Last modified: | 2019-10-23 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Crystal Structure of a Thermally Stable Rhodopsin Mutant.
J.Mol.Biol., 372, 2007
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2PED | | CRYSTALLOGRAPHIC MODEL OF 9-CIS-RHODOPSIN | | Descriptor: | Rhodopsin, ALPHA-D-MANNOSE, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Nakamichi, H., Okada, T. | | Deposit date: | 2007-04-02 | | Release date: | 2007-10-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Photoisomerization mechanism of rhodopsin and 9-cis-rhodopsin revealed by x-ray crystallography
Biophys.J., 92, 2007
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2X72 | | CRYSTAL STRUCTURE OF THE CONSTITUTIVELY ACTIVE E113Q,D2C,D282C RHODOPSIN MUTANT WITH BOUND GALPHACT PEPTIDE. | | Descriptor: | RHODOPSIN, GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... | | Authors: | Standfuss, J., Edwards, P.C., Dantona, A., Fransen, M., Xie, G., Oprian, D.D., Schertler, G.F.X. | | Deposit date: | 2010-02-22 | | Release date: | 2011-03-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The Structural Basis of Agonist Induced Activation in Constitutively Active Rhodopsin
Nature, 471, 2011
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2Z73 | |
3AYM | |
3AYN | | CRYSTAL STRUCTURE OF SQUID ISORHODOPSIN | | Descriptor: | Rhodopsin, RETINAL, PALMITIC ACID, ... | | Authors: | Murakami, M., Kouyama, T. | | Deposit date: | 2011-05-09 | | Release date: | 2011-08-17 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystallographic Analysis of the Primary Photochemical Reaction of Squid Rhodopsin
J.Mol.Biol., 413, 2011
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3C9L | |
3C9M | |
3CAP | | CRYSTAL STRUCTURE OF NATIVE OPSIN: THE G PROTEIN-COUPLED RECEPTOR RHODOPSIN IN ITS LIGAND-FREE STATE | | Descriptor: | Rhodopsin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... | | Authors: | Park, J.H., Scheerer, P., Hofmann, K.P., Choe, H.-W., Ernst, O.P. | | Deposit date: | 2008-02-20 | | Release date: | 2008-06-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of the ligand-free G-protein-coupled receptor opsin
Nature, 454, 2008
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3DQB | | CRYSTAL STRUCTURE OF THE ACTIVE G-PROTEIN-COUPLED RECEPTOR OPSIN IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM THE GALPHA SUBUNIT OF TRANSDUCIN | | Descriptor: | Rhodopsin, 11meric peptide form Guanine nucleotide-binding protein G(t) subunit alpha-1, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Scheerer, P., Park, J.H., Hildebrand, P.W., Kim, Y.J., Krauss, N., Choe, H.-W., Hofmann, K.P., Ernst, O.P. | | Deposit date: | 2008-07-09 | | Release date: | 2008-09-23 | | Last modified: | 2014-02-05 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of opsin in its G-protein-interacting conformation
Nature, 455, 2008
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3OAX | | CRYSTAL STRUCTURE OF BOVINE RHODOPSIN WITH BETA-IONONE | | Descriptor: | Rhodopsin, BETA-D-MANNOSE, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Makino, C.L., Riley, C.K., Looney, J., Crouch, R.K., Okada, T. | | Deposit date: | 2010-08-05 | | Release date: | 2011-01-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Binding of more than one retinoid to visual opsins
Biophys.J., 99, 2010
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3PQR | | CRYSTAL STRUCTURE OF METARHODOPSIN II IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM THE GALPHA SUBUNIT OF TRANSDUCIN | | Descriptor: | Rhodopsin, Guanine nucleotide-binding protein G(t) subunit alpha-1, RETINAL, ... | | Authors: | Choe, H.-W., Kim, Y.J., Park, J.H., Morizumi, T., Pai, E.F., Krauss, N., Hofmann, K.P., Scheerer, P., Ernst, O.P. | | Deposit date: | 2010-11-26 | | Release date: | 2011-03-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Crystal structure of metarhodopsin II.
Nature, 471, 2011
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3PXO | | CRYSTAL STRUCTURE OF METARHODOPSIN II | | Descriptor: | Rhodopsin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... | | Authors: | Choe, H.-W., Kim, Y.J., Park, J.H., Morizumi, T., Pai, E.F., Krauss, N., Hofmann, K.P., Scheerer, P., Ernst, O.P. | | Deposit date: | 2010-12-10 | | Release date: | 2011-03-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of metarhodopsin II.
Nature, 471, 2011
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4A4M | | CRYSTAL STRUCTURE OF THE LIGHT-ACTIVATED CONSTITUTIVELY ACTIVE N2C, M257Y,D282C RHODOPSIN MUTANT IN COMPLEX WITH A PEPTIDE RESEMBLING THE C-TERMINUS OF THE GALPHA-PROTEIN SUBUNIT (GACT) | | Descriptor: | RHODOPSIN, GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-3, RETINAL, ... | | Authors: | Deupi, X., Edwards, P., Singhal, A., Nickle, B., Oprian, D.D., Schertler, G.F.X., Standfuss, J. | | Deposit date: | 2011-10-17 | | Release date: | 2012-01-25 | | Last modified: | 2019-10-23 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Stabilized G Protein Binding Site in the Structure of Constitutively Active Metarhodopsin-II.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4BEY | | NIGHT BLINDNESS CAUSING G90D RHODOPSIN IN COMPLEX WITH GACT2 PEPTIDE | | Descriptor: | Rhodopsin, Guanine nucleotide-binding protein G(t) subunit alpha-1, SULFATE ION, ... | | Authors: | Singhal, A., Ostermaier, M.K., Vishnivetskiy, S.A., Panneels, V., Homan, K.T., Tesmer, J.J.G., Veprintsev, D., Deupi, X., Gurevich, V.V., Schertler, G.F.X., Standfuss, J. | | Deposit date: | 2013-03-12 | | Release date: | 2013-05-08 | | Last modified: | 2019-09-04 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Insights Into Congenital Stationary Night Blindness Based on the Structure of G90D Rhodopsin.
Embo Rep., 14, 2013
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4BEZ | | NIGHT BLINDNESS CAUSING G90D RHODOPSIN IN THE ACTIVE CONFORMATION | | Descriptor: | RHODOPSIN, ACETATE ION, SULFATE ION, ... | | Authors: | Singhal, A., Ostermaier, M.K., Vishnivetskiy, S.A., Panneels, V., Homan, K.T., Tesmer, J.J.G., Veprintsev, D., Deupi, X., Gurevich, V.V., Schertler, G.F.X., Standfuss, J. | | Deposit date: | 2013-03-12 | | Release date: | 2013-04-24 | | Last modified: | 2013-06-19 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Insights Into Congenital Stationary Night Blindness Based on the Structure of G90D Rhodopsin.
Embo Rep., 14, 2013
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4GBR | |
4J4Q | | CRYSTAL STRUCTURE OF ACTIVE CONFORMATION OF GPCR OPSIN STABILIZED BY OCTYLGLUCOSIDE | | Descriptor: | Rhodopsin, Guanine nucleotide-binding protein G(t) subunit alpha-1, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Park, J.H., Morizumi, T., Li, Y., Hong, J.E., Pai, E.F., Hofmann, K.P., Choe, H.W., Ernst, O.P. | | Deposit date: | 2013-02-07 | | Release date: | 2013-10-30 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Opsin, a structural model for olfactory receptors?
Angew.Chem.Int.Ed.Engl., 52, 2013
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4PHU | | CRYSTAL STRUCTURE OF HUMAN GPR40 BOUND TO ALLOSTERIC AGONIST TAK-875 | | Descriptor: | Free fatty acid receptor 1,Lysozyme, [(3S)-6-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy]biphenyl-3-yl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... | | Authors: | Srivastava, A., Yano, J.K., Hirozane, Y., Kefala, G., Snell, G., Lane, W., Gruswitz, F., Ivetac, A., Aertgeerts, K., Nguyen, J., Jennings, A., Okada, K. | | Deposit date: | 2014-05-07 | | Release date: | 2014-07-16 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.332 Å) | | Cite: | High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875.
Nature, 513, 2014
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4PXF | |
4S0V | | CRYSTAL STRUCTURE OF THE HUMAN OX2 OREXIN RECEPTOR BOUND TO THE INSOMNIA DRUG SUVOREXANT | | Descriptor: | Human Orexin receptor type 2 fusion protein to P. abysii Glycogen Synthase, [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone, OLEIC ACID | | Authors: | Yin, J., Kolb, P., Mobarec, J.C., Rosenbaum, D.M. | | Deposit date: | 2015-01-06 | | Release date: | 2015-01-14 | | Last modified: | 2017-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant.
Nature, 519, 2015
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4X1H | | OPSIN/G(ALPHA) PEPTIDE COMPLEX STABILIZED BY NONYL-GLUCOSIDE | | Descriptor: | Rhodopsin, C-terminal derived peptide of guanine nucleotide-binding protein G(t) subunit alpha-1, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Blankenship, E., Lodowski, D.T. | | Deposit date: | 2014-11-24 | | Release date: | 2015-11-04 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | The High-Resolution Structure of Activated Opsin Reveals a Conserved Solvent Network in the Transmembrane Region Essential for Activation.
Structure, 23, 2015
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4XT1 | | STRUCTURE OF A NANOBODY-BOUND VIRAL GPCR BOUND TO HUMAN CHEMOKINE CX3CL1 | | Descriptor: | G-protein coupled receptor homolog US28, Fractalkine, nanobody 7, ... | | Authors: | Burg, J.S., Jude, K.M., Waghray, D., Garcia, K.C. | | Deposit date: | 2015-01-22 | | Release date: | 2015-03-04 | | Last modified: | 2015-03-18 | | Method: | X-RAY DIFFRACTION (2.886 Å) | | Cite: | Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.
Science, 347, 2015
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4XT3 | | STRUCTURE OF A VIRAL GPCR BOUND TO HUMAN CHEMOKINE CX3CL1 | | Descriptor: | G-protein coupled receptor homolog US28, Fractalkine, UNKNOWN LIGAND, ... | | Authors: | Burg, J.S., Jude, K.M., Waghray, D., Garcia, K.C. | | Deposit date: | 2015-01-22 | | Release date: | 2015-03-04 | | Last modified: | 2015-03-18 | | Method: | X-RAY DIFFRACTION (3.801 Å) | | Cite: | Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.
Science, 347, 2015
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4ZJ8 | | STRUCTURES OF THE HUMAN OX1 OREXIN RECEPTOR BOUND TO SELECTIVE AND DUAL ANTAGONISTS | | Descriptor: | human OX1R fusion protein to P.abysii glycogen synthase, [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone, OLEIC ACID | | Authors: | Yin, J., Brautigam, C.A., Shao, Z., Clark, L., Harrell, C.M., Gotter, A.L., Coleman, P., Renger, J.J., Rosenbaum, D.M. | | Deposit date: | 2015-04-29 | | Release date: | 2016-03-09 | | Last modified: | 2016-04-13 | | Method: | X-RAY DIFFRACTION (2.751 Å) | | Cite: | Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors.
Nat.Struct.Mol.Biol., 23, 2016
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