8GGJ

Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #2 of 20)

Summary for 8GGJ

• Entry DOI: 10.2210/pdb8ggj/pdb
• Related: 8GFW
• EMDB information: 29986 40010
• Descriptor: Beta-2 adrenergic receptor, (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol (3 entities in total)
• Functional Keywords: gpcr, adrenergic, receptor, g protein, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 51976.48

Authors

Papasergi-Scott, M.M.,Skiniotis, G. (deposition date: 2023-03-08, release date: 2024-03-06, Last modification date: 2024-03-27)

• Primary citation: Papasergi-Scott, M.M.,Perez-Hernandez, G.,Batebi, H.,Gao, Y.,Eskici, G.,Seven, A.B.,Panova, O.,Hilger, D.,Casiraghi, M.,He, F.,Maul, L.,Gmeiner, P.,Kobilka, B.K.,Hildebrand, P.W.,Skiniotis, G.; Time-resolved cryo-EM of G-protein activation by a GPCR.; Nature, 2024; PubMed: 38480881; DOI: 10.1038/s41586-024-07153-1

Experimental method

ELECTRON MICROSCOPY (3.5 Å)