7BRE
| The crystal structure of MLL2 in complex with ASH2L and RBBP5 | Descriptor: | Histone-lysine N-methyltransferase 2B, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Li, Y, Zhao, L, Chen, Y. | Deposit date: | 2020-03-28 | Release date: | 2020-07-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.803 Å) | Cite: | Crystal Structure of MLL2 Complex Guides the Identification of a Methylation Site on P53 Catalyzed by KMT2 Family Methyltransferases. Structure, 28, 2020
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5F6L
| The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L | Descriptor: | Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Li, Y, Lei, M, Chen, Y. | Deposit date: | 2015-12-06 | Release date: | 2016-02-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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2VOK
| Murine TRIM21 | Descriptor: | 52 KDA RO PROTEIN | Authors: | Keeble, A.H, Khan, Z, Forster, A, James, L.C. | Deposit date: | 2008-02-19 | Release date: | 2008-04-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Trim21 is an Igg Receptor that is Structurally, Thermodynamically, and Kinetically Conserved. Proc.Natl.Acad.Sci.USA, 105, 2008
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5F6K
| Crystal structure of the MLL3-Ash2L-RbBP5 complex | Descriptor: | Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Li, Y, Lei, M, Chen, Y. | Deposit date: | 2015-12-06 | Release date: | 2016-02-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.411 Å) | Cite: | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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2WL1
| Pyrin PrySpry domain | Descriptor: | 1,2-ETHANEDIOL, PYRIN, THIOCYANATE ION | Authors: | Weinert, C, Mittl, P.R, Gruetter, M.G. | Deposit date: | 2009-06-19 | Release date: | 2009-10-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | The Crystal Structure of Human Pyrin B30.2 Domain: Implications for Mutations Associated with Familial Mediterranean Fever. J.Mol.Biol., 394, 2009
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4V1P
| BTN3 Structure | Descriptor: | BUTYROPHILIN SUBFAMILY 3 MEMBER A1 | Authors: | James, L.C. | Deposit date: | 2014-09-30 | Release date: | 2015-07-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Activation of Human Gammadelta T Cells by Cytosolic Interactions of Btn3A1 with Soluble Phosphoantigens and the Cytoskeletal Adaptor Periplakin. J.Immunol., 194, 2015
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6FLN
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6FLM
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6SWY
| Structure of active GID E3 ubiquitin ligase complex minus Gid2 and delta Gid9 RING domain | Descriptor: | Glucose-induced degradation protein 8, Protein FYV10,Protein FYV10,Protein FYV10,Protein FYV10,Protein FYV10,Protein FYV10,Protein FYV10, Vacuolar import and degradation protein 24, ... | Authors: | Qiao, S, Prabu, J.R, Schulman, B.A. | Deposit date: | 2019-09-24 | Release date: | 2019-11-20 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly Mol.Cell, 77, 2020
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6SJH
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8A8X
| TRIM7 PRYSPRY in complex with a MNV1-NS3 peptide HDDFGLQ | Descriptor: | E3 ubiquitin-protein ligase TRIM7, MNV1-NS3 C term peptide | Authors: | Luptak, J. | Deposit date: | 2022-06-24 | Release date: | 2022-07-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing. Viruses, 14, 2022
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4WVM
| Stonustoxin structure | Descriptor: | Stonustoxin subunit alpha, Stonustoxin subunit beta | Authors: | Ellisdon, A.M, Panjikar, S, Whisstock, J.C, McGowan, S. | Deposit date: | 2014-11-06 | Release date: | 2015-12-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Stonefish toxin defines an ancient branch of the perforin-like superfamily. Proc.Natl.Acad.Sci.USA, 112, 2015
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6UMA
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6UMB
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8BV0
| Binary complex between the NB-ARC domain from the Tomato immune receptor NRC1 and the SPRY domain-containing effector SS15 from the potato cyst nematode | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, NRC1, Truncated secreted SPRY domain-containing protein 15 (Fragment) | Authors: | Contreras, M.P, Pai, H, Muniyandi, S, Toghani, A, Lawson, D.M, Tumtas, Y, Duggan, C, Yuen, E.L.H, Stevenson, C.E.M, Harant, A, Wu, C.H, Bozkurt, T.O, Kamoun, S, Derevnina, L. | Deposit date: | 2022-12-01 | Release date: | 2022-12-21 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Resurrection of plant disease resistance proteins via helper NLR bioengineering. Sci Adv, 9, 2023
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8A5L
| TRIM7 PRYSPRY in complex with a 2BC peptide TIEALFQ | Descriptor: | 2BC peptide TIEALFQ, D(-)-TARTARIC ACID, E3 ubiquitin-protein ligase TRIM7 | Authors: | Luptak, J. | Deposit date: | 2022-06-15 | Release date: | 2022-07-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.622 Å) | Cite: | TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing. Viruses, 14, 2022
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8A5M
| TRIM7 PRYSPRY in complex with a MNV1-NS6 peptide LEALEFQ | Descriptor: | E3 ubiquitin-protein ligase TRIM7, MNV1-NS6 peptide LEALEFQ, PHOSPHATE ION | Authors: | Luptak, J. | Deposit date: | 2022-06-15 | Release date: | 2022-07-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.918 Å) | Cite: | TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing. Viruses, 14, 2022
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2FBE
| Crystal Structure of the PRYSPRY-domain | Descriptor: | PREDICTED: similar to ret finger protein-like 1 | Authors: | Gruetter, C, Briand, C, Capitani, G, Mittl, P.R, Gruetter, M.G. | Deposit date: | 2005-12-09 | Release date: | 2006-01-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Structure of the PRYSPRY-domain: Implications for autoinflammatory diseases Febs Lett., 580, 2006
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3ZO0
| Mouse IgG2a in complex with mouse TRIM21 PRYSPRY | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE TRIM21, IG GAMMA-2A CHAIN C REGION, A ALLELE, ... | Authors: | James, L.C. | Deposit date: | 2013-02-19 | Release date: | 2013-05-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Trim21 is an Igg Receptor that is Structurally, Thermodynamically, and Kinetically Conserved. Proc.Natl.Acad.Sci.USA, 105, 2008
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4B3N
| Crystal structure of rhesus TRIM5alpha PRY/SPRY domain | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MALTOSE-BINDING PERIPLASMIC PROTEIN, TRIPARTITE MOTIF-CONTAINING PROTEIN 5, ... | Authors: | Yang, H, Ji, X, Zhao, Q, Xiong, Y. | Deposit date: | 2012-07-25 | Release date: | 2012-10-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural Insight Into HIV-1 Capsid Recognition by Rhesus Trim5Alpha Proc.Natl.Acad.Sci.USA, 109, 2012
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4N7I
| Crystal Structure of Intracellular B30.2 Domain of BTN3A1 | Descriptor: | BETA-MERCAPTOETHANOL, Butyrophilin subfamily 3 member A1, CHLORIDE ION, ... | Authors: | Sandstrom, A, Adams, E.J. | Deposit date: | 2013-10-15 | Release date: | 2014-04-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.4015 Å) | Cite: | The Intracellular B30.2 Domain of Butyrophilin 3A1 Binds Phosphoantigens to Mediate Activation of Human V gamma 9V delta 2 T Cells. Immunity, 40, 2014
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2IWG
| COMPLEX BETWEEN THE PRYSPRY DOMAIN OF TRIM21 AND IGG FC | Descriptor: | 52 KDA RO PROTEIN, IG GAMMA-1 CHAIN C, alpha-L-fucopyranose, ... | Authors: | James, L.C, Keeble, A.H, Rhodes, D.A, Trowsdale, J. | Deposit date: | 2006-06-30 | Release date: | 2007-03-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Basis for Pryspry-Mediated Tripartite Motif (Trim) Protein Function. Proc.Natl.Acad.Sci.USA, 104, 2007
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4N7U
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6E2H
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4B8E
| PRY-SPRY domain of Trim25 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, E3 UBIQUITIN/ISG15 LIGASE TRIM25 | Authors: | Kershaw, N.J, D'Cruz, A.A, Nicola, N.A, Nicholson, S.E, Babon, J.J. | Deposit date: | 2012-08-27 | Release date: | 2013-09-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.779 Å) | Cite: | Crystal Structure of the Trim25 B30.2 (Pryspry) Domain: A Key Component of Antiviral Signaling. Biochem.J., 456, 2013
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